Safe and Successful Treatment of Acne Vulgaris with Isotretinoin in a Patient with Chronic Granulomatous Disease
Article first published online: 4 OCT 2011
© 2012 Wiley Periodicals, Inc.
Volume 29, Issue 5, pages 662–663, September/October 2012
How to Cite
Alonso-de-Celada, R. M. and de-Lucas Laguna, R. (2012), Safe and Successful Treatment of Acne Vulgaris with Isotretinoin in a Patient with Chronic Granulomatous Disease. Pediatric Dermatology, 29: 662–663. doi: 10.1111/j.1525-1470.2011.01510.x
- Issue published online: 13 SEP 2012
- Article first published online: 4 OCT 2011
Abstract: Isotretinoin for acne vulgaris in the setting of chronic granulomatous disease (CGD) is a controversial therapeutic option. In this inherited immunodeficiency, inefficient tissue responses to bacteria and fungi lead to chronic and recurrent infections. Isotretinoin is known to be associated with several mucocutaneous side effects that could worsen the immune response in individuals with CGD. We report the fourth published case of acne vulgaris treated with isotretinoin in an individual with CGD, with a safe and successful outcome.