Multiple Cutaneous Plexiform Schwannomas as Initial Presentation of Neurofibromatosis 2 in a 9-Year-Old
Article first published online: 9 SEP 2011
© 2011 Wiley Periodicals, Inc.
Volume 29, Issue 4, pages 536–538, July/August 2012
How to Cite
Nguyen, T. V., Matthews, M. R., Barrera, F. F. and Browning, J. C. (2012), Multiple Cutaneous Plexiform Schwannomas as Initial Presentation of Neurofibromatosis 2 in a 9-Year-Old. Pediatric Dermatology, 29: 536–538. doi: 10.1111/j.1525-1470.2011.01532.x
- Issue published online: 3 JUL 2012
- Article first published online: 9 SEP 2011
Abstract: Neurofibromatosis 2 (NF2) is an autosomal-dominant disease caused by genetic mutations of the NF2 gene on chromosome 22. Patients are often diagnosed according to the presence of bilateral vestibular schwannomas and other tumors in the brain and spinal cord. In children, NF2 can present early with ocular findings and cutaneous tumors. We report here a 9-year-old girl who presented with multiple pigmented, slightly tender plaques on her scalp, face, and back that were revealed by histopathology to be plexiform schwannomas. We suspected NF2 and sent the patient’s blood for genetic testing, which confirmed our diagnosis.