Erythema Dyschromicum Perstans in a Japanese Child
Article first published online: 8 NOV 2011
© 2011 Wiley Periodicals, Inc.
Volume 29, Issue 5, pages 637–640, September/October 2012
How to Cite
Oiso, N., Tsuruta, D., Imanishi, H., Kobayashi, H. and Kawada, A. (2012), Erythema Dyschromicum Perstans in a Japanese Child. Pediatric Dermatology, 29: 637–640. doi: 10.1111/j.1525-1470.2011.01567.x
- Issue published online: 13 SEP 2012
- Article first published online: 8 NOV 2011
Abstract: Erythema dyschromicum perstans (EDP) is asymptomatic slate-gray to blue-brown macules. Idiopathic eruptive macular pigmentation is asymptomatic brown nonconfluent macules. We describe electron microscopic studies of a 9-year-old Japanese girl with EDP. The ultrastructural figures indicated that the production of immature, small, irregular-shaped melanosomes in melanocytes and peripheral localization of melanosomes in keratinocytes caused the clinical appearance of EDP. The ultrastructural evidence distinguishes EDP from idiopathic eruptive macular pigmentation and suggests a distinct pathogenesis of the disease.