Photodynamic Therapy in a Teenage Girl with Xeroderma Pigmentosum Type C

  1. DAVID M. LARSON M.D.1,
  2. BARI B. CUNNINGHAM M.D.,†2

Article first published online: 26 JAN 2012

DOI: 10.1111/j.1525-1470.2011.01657.x

Issue

Pediatric Dermatology

Pediatric Dermatology

Volume 29, Issue 3, pages 373–374, May/June 2012

Additional Information

How to Cite

LARSON, D. M. and CUNNINGHAM, B. B. (2012), Photodynamic Therapy in a Teenage Girl with Xeroderma Pigmentosum Type C. Pediatric Dermatology, 29: 373–374. doi: 10.1111/j.1525-1470.2011.01657.x

Author Information

  1. 1

    Department of Psychiatry

  2. 2

    Departments of Pediatrics and Medicine, University of California at San Diego, San Diego, California

*Address correspondence to David Larson M.D., Departments of Pediatrics and Medicine, University of California at San Diego, San Diego, California, 9500 Gillman Dr., #9116A, La Jolla, CA 92093, or e-mail: dmlarson@usc.edu.

Publication History

  1. Issue published online: 17 MAY 2012
  2. Article first published online: 26 JAN 2012

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Abstract:  Despite aggressive sun protection, most individuals with xeroderma pigmentosum (XP) develop cutaneous neoplasia, including actinic keratoses. We describe the case of a 16-year-old girl with XP type C treated safely with photodynamic therapy (PDT). Although there is little if any evidence in the literature supporting the use of aminolevulinic acid PDT in individuals with XP, they may be the ideal candidates for PDT treatment because the profound post-treatment photosensitivity and strict post-therapy sun avoidance necessitated by PDT treatment is already part of the everyday lifestyle of people with XP.

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