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Granulomatous Variant of Giant Centrifugal Miliaria Profunda


Address correspondence to Bhavana R. Doshi, M.D., C/O Uday Khopkar, Department of Dermatology, Seth G.S. Medical College and K.E.M. Hospital, Parel, Mumbai 400012, India, or e-mail:


Abstract:  Two infants presented with multiple asymptomatic papules and geographic and annular plaques over the extensor aspect of the upper and lower extremities and trunk. Skin biopsy of both lesions showed plugged and hyperplastic dilated acrosryingia and deep dermal ducts, along with granulomatous inflammatory reaction. These lesions showed self-healing with complete resolution. A previous report described similar clinical and histopathologic features and labeled it giant centrifugal miliaria profunda. Because of the large granulomatous plaques and deep infiltrate, we propose that it was a granulomatous variant of giant centrifugal miliaria profunda. We report these cases for their rarity and self-healing nature.