Generalized Pustular Psoriasis in a Child: Observation of Long-Term Combination Therapy with Etretinate and Calcipotriol for 16 Years
Article first published online: 13 MAR 2012
© 2012 Wiley Periodicals, Inc.
Volume 29, Issue 2, pages 206–208, March/April 2012
How to Cite
Umezawa, Y., Mabuch, T. and Ozawa, A. (2012), Generalized Pustular Psoriasis in a Child: Observation of Long-Term Combination Therapy with Etretinate and Calcipotriol for 16 Years. Pediatric Dermatology, 29: 206–208. doi: 10.1111/j.1525-1470.2011.01687.x
- Issue published online: 13 MAR 2012
- Article first published online: 13 MAR 2012
Abstract: Generalized pustular psoriasis (GPP) is a rare condition in young children. It is difficult to treat and may require long-term systemic therapy. We report the long-term course of a 3-year-old boy whose onset of psoriasis dated to age 7 months. He was treated with etretinate and psoralen plus ultraviolet A therapy initially and then with etretinate alone, and at age 12, topical calcipotriol was added. At the age of 19, he had been taking oral retinoids for 16 years, with a mean dose of etretinate of 0.22 mg/kg per day, a total amount of approximately 37 g, without evidence of stunted growth, ligamentous calcification, hyperostosis, or hepatic toxicity.