Wet-Wrap Treatment in Children with Atopic Dermatitis: A Practical Guideline


  • Cetomacrogol cream is used as a neutral emollient and available on its own or combined with petrolatum in different concentrations to make it more greasy. It contains cetomacrogol wax.

Address correspondence to Arjan C. A. Devillers, M.D., Ph.D., Maasstad Hospital, P.O. Box 9100, 3007 AC, Rotterdam, The Netherlands, or e-mail: devillersa@maasstadziekenhuis.nl.


Abstract:  Treatment of children with severe atopic dermatitis (AD) can be especially challenging because several possible intervention treatments have (relative) contraindications in childhood. In recent years, wet-wrap treatment (WWT) has been advocated as a relatively safe and efficacious intervention in children with severe or refractory AD. The goal of this article is to provide a practical guideline as a starting point for clinicians who are interested in using WWT in their own clinical practice. We will address several practical issues surrounding the use of WWT by describing our own experiences, supplemented with data from the literature.