A Case of Pemphigus Herpetiformis Occurring in a 9-Year-Old Boy


Address correspondence to Diya F. Mutasim, M.D., Department of Dermatology, College of Medicine, University of Cincinnati, PO Box 670592, Cincinnati, OH 45267, USA, or e-mail: diya.mutasim@uc.edu.


Abstract:  Pemphigus herpetiformis (PH) is a rare autoimmune vesiculobullous disease. It clinically mimics dermatitis herpetiformis and has immunofluorescent findings typical of pemphigus. PH occurs in adults more commonly than children and is often effectively treated with dapsone. We report a case of PH occurring in a 9-year-old boy that was refractory to dapsone and to various other steroid-sparing medications but resolved with methotrexate.