Working Group on Vascular Anomalies Rotterdam team.
CLINICAL AND LABORATORY INVESTIGATION
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Infantile Hemangioma: Treatment with Short Course Systemic Corticosteroid Therapy as an Alternative for Propranolol
Article first published online: 7 SEP 2012
DOI: 10.1111/j.1525-1470.2012.01846.x
© 2012 Wiley Periodicals, Inc.
Additional Information
How to Cite
Nieuwenhuis, K., de Laat, P. C. J., Janmohamed, S. R., Madern, G. C. and Oranje, A. P. (2013), Infantile Hemangioma: Treatment with Short Course Systemic Corticosteroid Therapy as an Alternative for Propranolol. Pediatric Dermatology, 30: 64–70. doi: 10.1111/j.1525-1470.2012.01846.x
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Working Group on Vascular Anomalies Rotterdam team.
Publication History
- Issue published online: 15 JAN 2013
- Article first published online: 7 SEP 2012
References
- 1. Color atlas of vascular tumors and vascular malformations. Paris: Cambridge University Press, 2007.
- 2, , et al.Propranolol for severe hemangiomas of infancy. N Engl J Med2008;358:2649–2651.
- 3, , et al.Propranolol vs corticosteroids for infantile hemangiomas: a multicenter retrospective analysis. Arch Dermatol2011;147:1371–1376.
- 4, , . A randomized controlled trial of propranolol for infantile hemangiomas. Pediatrics2011;128:e259–e266.
- 5, . Propranolol for infantile haemangiomas: insights into the molecular mechanisms of action. Br J Dermatol2010;163:269–274.
- 6. Update on vascular tumors of infancy. Curr Opin Pediatr2010;22:432–437.
- 7, , . Propranolol treatment for hemangioma of infancy: risks and recommendations. Pediatr Dermatol2009;26:610–614.
- 8, , et al.Oral propranolol therapy for infantile hemangiomas beyond the proliferation phase: a multicenter retrospective study. Pediatr Dermatol2011;28:94–98.
- 9, , et al.Oral corticosteroid use is effective for cutaneous hemangiomas: an evidence-based evaluation. Arch Dermatol2001;137:1208–1213.
- 10, , . Complications of systemic corticosteroid therapy for problematic hemangioma. Plast Reconstr Surg1999;104:1616–1623.
- 11, , . Management of parotid hemangioma in 100 children. Plast Reconstr Surg2004;113:53–60.
- 12, , et al.Corticosteroid suppression of VEGF-A in infantile hemangioma-derived stem cells. N Engl J Med2010;362:1005–1013.
- 13, . Hemangiomas of infancy. J Am Acad Dermatol2003;48:477–493, quiz 494–476.
- 14, , et al.Pulse methylprednisolone therapy for threatening periocular haemangiomas of infancy. Acta Derm Venereol2006;86:429–432.
- 15, . Craniofacial cavernous hemangioma: successful treatment with methylprednisolone. Acta Dermatovenerol Alp Panonica Adriat2005;14:49–52.
- 16, , et al.Adverse effects of systemic glucocorticosteroid therapy in infants with hemangiomas. Arch Dermatol2004;140:963–969.
- 17, , et al.Oral versus high-dose pulse corticosteroids for problematic infantile hemangiomas: a randomized, controlled trial. Pediatrics2007;119:e1239–e1247.
- 18, , et al.Scoring the proliferative activity of haemangioma of infancy: the Haemangioma Activity Score (HAS). Clin Exp Dermatol2011;36:715–723.
- 19, , et al.An unusual complication of the treatment of a hemangioma. Ann Plast Surg2002;48:83–87.
- 20, , . Pneumocystis carinii pneumonia in a 3-month-old infant receiving high-dose corticosteroid therapy for airway hemangiomas. Mayo Clin Proc2004;79:243–245.
- 21, , et al.Infantile hemangiomas: current knowledge, future directions. Proceedings of a research workshop on infantile hemangiomas, April 7–9, 2005, Bethesda, Maryland, USA. Pediatr Dermatol2005;22:383–406.Direct Link:
- 22, , et al.Propranolol versus prednisone in the treatment of infantile hemangiomas: a retrospective comparative study. Pediatr Dermatol2011;28:649–654.
- 23, , et al.Corticosteroid suppression of VEGF-A in infantile hemangioma-derived stem cells. N Engl J Med2010;362:1005–1013.

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