The Impact of a Suspicious Prostate Biopsy on Patients' Psychological, Socio-behavioral, and Medical Care Outcomes
Version of Record online: 12 MAY 2006
Journal of General Internal Medicine
Volume 21, Issue 7, pages 715–721, July 2006
How to Cite
Fowler, F. J., Barry, M. J., Walker-Corkery, B., Caubet, J.-F., Bates, D. W., Lee, J. M., Hauser, A. and McNaughton-Collins, M. (2006), The Impact of a Suspicious Prostate Biopsy on Patients' Psychological, Socio-behavioral, and Medical Care Outcomes. Journal of General Internal Medicine, 21: 715–721. doi: 10.1111/j.1525-1497.2006.00464.x
- Issue online: 12 MAY 2006
- Version of Record online: 12 MAY 2006
- Manuscript received July 20, 2005Initial editorial decision August 21, 2005Final acceptance February 23, 2006
- prostate biopsy;
- prostate cancer;
OBJECTIVE: To evaluate the psychological, socio-behavioral, and medical implications of apparently false-positive prostate cancer screening results.
METHODS: One hundred and twenty-one men with a benign prostate biopsy performed in response to a suspicious screening test (biopsy group) and 164 men with a normal prostate-specific antigen (PSA) test result (normal PSA group) responded to a questionnaire 6 weeks, 6 and 12 months after their biopsy or PSA test.
RESULTS: The mean (±SD) age of respondents was 61±9 years (range, 41 to 88 years). One year later, 26% (32/121) of men in the biopsy group reported having worried “a lot” or “some of the time” that they may develop prostate cancer, compared with 6% (10/164) in the normal PSA group (P<.001). Forty-six percent of the biopsy group reported thinking their wife or significant other was concerned about prostate cancer, versus 14% in the normal PSA group (P<.001). Medical record review showed that biopsied men were more likely than those in the normal PSA group to have had at least 1 follow-up PSA test over the year (73% vs 42%, P<.001), more likely to have had another biopsy (15% vs 1%, P<.001), and more likely to have visited a urologist (71% vs 13%, P<.001).
CONCLUSION: One year later, men who underwent prostate biopsy more often reported worrying about prostate cancer. In addition, there were related psychological, socio-behavioral, and medical care implications. These hidden tolls associated with screening should be considered in the discussion about the benefits and risks of prostate cancer screening.