Mock Circulatory System for the Evaluation of Left Ventricular Assist Devices, Endoluminal Prostheses, and Vascular Diseases


  • Presented in part at the 4th Latin American Congress for Artificial Organs and Biomaterials held August 8–11, 2006 in Caxambu, Brazil.

Dr. Daniel Legendre, Department of Mechanical Engineering, Escola Politécnica, University of São Paulo, Av. Prof. Luciano Gualberto, 380, trav. 3, 05508-900, São Paulo, SP, Brazil. E-mail:


Abstract:  A new digital computer mock circulatory system has been developed in order to replicate the physiologic and pathophysiologic characteristics of the human cardiovascular system. The computer performs the acquisition of pressure, flow, and temperature in an open loop system. A computer program has been developed in Labview programing environment to evaluate all these physical parameters. The acquisition system was composed of pressure, flow, and temperature sensors and also signal conditioning modules. In this study, some results of flow, cardiac frequencies, pressures, and temperature were evaluated according to physiologic ventricular states. The results were compared with literature data. In further works, performance investigations will be conducted on a ventricular assist device and endoprosthesis. Also, this device should allow for evaluation of several kinds of vascular diseases.