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Osteal Complications as First Manifestation in a Patient with Primary Sjögren's Syndrome and with Associated Distal Tubular Acidosis (Type 1) and Chronic Renal Insufficiency
Article first published online: 15 APR 2004
DOI: 10.1111/j.1526-0968.2003.00122.x
1744-9987/asset/cover.gif?v=1&s=3eb27d139be57b628f0095d9e8ffd48d6a5e7b36 "Therapeutic Apheresis and Dialysis")
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How to Cite
Díaz Rodríguez, C., González Rivero, C., Trinidad San José, J., Del Río Romero, D., Moreno Fernández, A. and Granja Romero, E. (2004), Osteal Complications as First Manifestation in a Patient with Primary Sjögren's Syndrome and with Associated Distal Tubular Acidosis (Type 1) and Chronic Renal Insufficiency. Therapeutic Apheresis and Dialysis, 8: 160–163. doi: 10.1111/j.1526-0968.2003.00122.x
Publication History
- Issue published online: 15 APR 2004
- Article first published online: 15 APR 2004
- Received May 2003; revised September 2003.
- Abstract
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Keywords:
- Distal renal tubular acidosis;
- Osteomalacia;
- Renal insufficiency;
- Sjögren's Syndrome
Abstract: Renal affection is among the complications associated with the Sjögren's Syndrome. Tubulo-interstitial nephritis constitutes the most frequent renal lesion and distal tubular acidosis (Type 1) is the most important clinical manifestation of this tubular dysfunction, although the occurrence of chronic renal insufficiency is not an uncommon finding in the presence of distal renal tubular acidosis. Osteomalacia is a clinical consequence of tubular acidosis caused by buffering of H+ in the bone. We present the case of a woman with osteal complication a year before being diagnosed with primary Sjögren's Syndrome and with distal tubular acidosis and renal insufficiency associated at diagnosis.