Hemicrania and Ipsilateral Trunk and Limb Symptoms




One hundred and eleven cases of migraine seen over 412 years were studied. A useful diagnostic feature was motor or sensory symptoms ipsilateral to hemicrania. It is suggested that this lateralization is inherent in the response of the sympathetic nervous system to a generalized body reaction, but the response is predominantly peripheral and confined to adrenoceptive components unilaterally. This hypothesis should be tested by assessing the frequency of ipsilateral symptoms in common and classic migraine, and by neuropharmacologic tests.