The Platelet Release Reaction During Migraine Attacks
Article first published online: 23 JUN 2005
Headache: The Journal of Head and Face Pain
Volume 19, Issue 6, pages 323–327, September 1979
How to Cite
Gawel, M., Burkitt, M. and Rose, F. C. (1979), The Platelet Release Reaction During Migraine Attacks. Headache: The Journal of Head and Face Pain, 19: 323–327. doi: 10.1111/j.1526-4610.1979.hed1906323.x
- Issue published online: 23 JUN 2005
- Article first published online: 23 JUN 2005
- Accepted for Publication: June 9, 1979
- Cited By
An investigation is reported of serum levels of Beta Thromboglobulin (BTG), a platelet release reaction specific protein, and the stable metabolites of thromboxane B2 and prostacyclin during and between migraine attacks, and in age and sex matched controls.
The level of BTG in plasma from controls was 61.3 ngml (± 26.15), in patients during migraine attacks 127.69 ngml (± 82.8) whilst between attacks the level was 69.06 ngml.
No changes were observed in the levels of the stable metabolite of thromboxane B2 and prostacyclin.
The significant rise in BTG (p = < .02) during migraine attacks indicates that the platelet release reaction occurs during the headache phase.