Bilateral blood volume pulse response recordings from the fronto-temporal artery were obtained from a migraineur during a headache state, in a headache free state, and for several days following one headache in order to assess for general vasomotor disregulation. Recordings were also obtained at various times prior to the onset of several independent headaches. The results indicated marked variability for both within session recordings and between session recordings for the migraineur. The recordings from the non-migraineur, who was matched to the migraineur on several relevant factors, indicated greater consistency of the blood volume pulse both within and between sessions than was observed with the migraineur. The findings lend support to previous research which indicates that the vasomotor response system of migraineurs may be in a chronic state of disregulation relative to the vasomotor response system of non-migraineurs.