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SYNOPSIS

The incidence of smoking in a group of male cluster headache patients (95%) was significantly (P<0.001) greater than in a matched group of male migrainous patients (26%). Both groups had significantly lower platelet monoamine oxidase activity than controls. This finding may be connected genetically with certain personality characteristics, including predisposition to smoke. It is possible that migrainous patients smoke less than those with cluster headache because the process of smoking has a greater tendency to provoke their headache attacks.