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SYNOPSIS

The autonomic nervous system functions of 49 young migraine patients, aged from 11 to 22 years, wereinvestigated during headache-free intervals by utilizing a number of cardiovascular reflexes as indices.Twenty-five healthy subjects of similar age served as a control group. The pulse rate (R-R-interval)variation was registered in normal and deep breathing, during the Valsalva manoeuvre, and in anorthostatic test (a tilt table was used); and the blood pressure measurements were performed in anorthostatic test and during an isometric work test. There were no significant differences between the groupof young migraine patients and the control group. Furthermore, all numeric mean values were in thenormal limits given in the literature; only incidental abnormal values were encountered, and even then inboth groups. Moreover, the cardiovascular reflex responses of various subgroups of migraine patients(common-classic, frequent -infrequent attacks, patients with or without autonomic nervous systemdysfunction signs during attacks, normal-abnormal EEGs), did not significantly differ from each otherduring this interictal recording period. The results suggest intact autonomic nervous system functions inyoung migraine patients during headache free intervals.