This transverse statistical study deals with a series of 412 patients with migraine ranging between less than one year and more than thirty years of evolution. The chronological and clinical characteristics and the therapeutic results vary with the duration of the condition. In long standing migraine, there are less typical migrainous characteristics (prodromes, hemicranias). Classic migraine has a shorter evolution than common migraine. Menopause seems to have an ameliorating effect on migraine. Whatever the duration of migraine neurotic conditions are the most common pathological previous history. Even in long-standing migraine, the erget derivatives are the most efficient antimigrainous drugs.