Autonomic Dysfunction in Migraine: A Survey of 188 Patients

  1. H. Havanka-Kanniainen,
  2. U. Tolonen,
  3. V.V. Myllylä

Article first published online: 22 JUN 2005

DOI: 10.1111/j.1526-4610.1988.hed2807465.x

Issue

Headache: The Journal of Head and Face Pain

Headache: The Journal of Head and Face Pain

Volume 28, Issue 7, pages 465–470, August 1988

Additional Information

How to Cite

Havanka-Kanniainen, H., Tolonen, U. and Myllylä, V. (1988), Autonomic Dysfunction in Migraine: A Survey of 188 Patients. Headache: The Journal of Head and Face Pain, 28: 465–470. doi: 10.1111/j.1526-4610.1988.hed2807465.x

Author Information

  1. Department of Neurology, University of Oulu, SF-90220 Oulu, Finland.

Publication History

  1. Issue published online: 22 JUN 2005
  2. Article first published online: 22 JUN 2005
  3. Accepted for Publication: May 31, 1988

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SYNOPSIS

Autonomic nervous system functions were studied in 188 patients with migraine during headache free intervals by measuring cardiovascular reflex responses. Eighty-five healthy subjects served as a control group.

Pulse rate (R-R- interval) variation in normal and deep breathing, during Valsalva manoeuvre and orthostatic test was diminished in migraine patients. Diastolic blood pressure rises in orthostatic test and isometric work test were lower than in the controls. The results of patients with classic and common migraine did not deviate from each other. The same was true for the results of the female and male patients.

The results of the patients with frequent migraine attacks (>4/month) showed more severe disturbance than those with infrequent attacks. Disturbances gradually developed with age, being minimal or totally lacking in young migraine patients. The results confirm the development of sympathetic and parasympathetic hypofunction in migraine patients during the course of the disorder.

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