1Associate Professor of Neurology.
Long-latency Auditory Event Related Potentials in Migraine†
Article first published online: 21 JUN 2005
Headache: The Journal of Head and Face Pain
Volume 29, Issue 4, pages 239–241, April 1989
How to Cite
Drake, M. E., Pakalnis, A. and Padamadan, H. (1989), Long-latency Auditory Event Related Potentials in Migraine. Headache: The Journal of Head and Face Pain, 29: 239–241. doi: 10.1111/j.1526-4610.1989.hed22904239.x
Presented in part at the 41st Annual Meeting, Southern EEG Society, Nashville, TN, June 18, 1988.
Supported in part by The Clinical Neurophysiology Development Fund, The Ohio State University.
- Issue published online: 21 JUN 2005
- Article first published online: 21 JUN 2005
- Accepted for Publication: February 3, 1989.
- Cited By
The pathophysiology of migraine and its associated perceptual symptoms remains controversial. We recorded long-latency auditory event related potentials (AEPs) in 30 unmedicated patients with common migraine, and compared them to 20 controls. 1,000 and 3,000 Hz tones were presented in an 80:20 ratio at 75 dB SL. 200 responses were recorded and replicated from Cz-A1 +A2, with filter band-pass of I - 100 Hz, analysis time of 1,000 ms., and interstimulus interval of 1.1 second.
N100, P200, and N200 ERP components did not differ in latency or amplitude between migraine patients and controls. P300 was longer in latency among those with common migraine, and P300 amplitude was significantly reduced (P>0.05). These findings suggest that migraine may have a central mechanism, and that migraineurs may have a difference in task involvement or perception which may influence their clinical course and response to therapy.