This study was supported in part by a grant from the National Migraine Foundation and also from the Milton W. Feld Charitable Trust.
Clinical and Electrophysiological Responses to Dietary Challenge in Migraineurs †
Version of Record online: 21 JUN 2005
Headache: The Journal of Head and Face Pain
Volume 29, Issue 3, pages 180–186, March 1989
How to Cite
Lai, C.-W., Dean, P., Ziegler, D. K. and Hassanein, R. S. (1989), Clinical and Electrophysiological Responses to Dietary Challenge in Migraineurs . Headache: The Journal of Head and Face Pain, 29: 180–186. doi: 10.1111/j.1526-4610.1989.hed2903180.x
Parts of this study were presented at the annual meeting of the American Association for the Study of Headache, June, 1987,(Quebec City, Canada).
- Issue online: 21 JUN 2005
- Version of Record online: 21 JUN 2005
- Accepted for Publication: November 1, 1988
- Cited By
Thirty eight patients with a history of diet-induced migraine were studied with recording of clinical responses, electro-encephalography in resting state, in response to photic stimulation, and to hyperventilation and visual evoked potentials. Tests were carried out on an initial baseline day and on a second day, after challenge with chocolate, red wine, cheese, and fasting.
Lateralized headache occurred in sixteen subjects (42%), four with scintillating scotomata. Electroencephalograms were abnormal on Day I and/or Day 2 in twelve subjects (32%), most abnormalities being non-specific slow waves. In three cases there were paroxysmal features.
Electroencephalographic response to hyperventilation was calibrated and was found to be exaggerated in eight subjects (21%) on either Day 1 or Day 2; such response was not related to the occurrence of a headache. Photic simulation showed high frequency driving response (so called “H” response) in all 16 individuals who developed headache but in only 14 out of 22 (64%) who did not (p<0.01). Pattern reversal visual evoked responses were normal and failed to show any difference in latency or amplitude between headache responders and non-responders.