This paper is the winner of the 1989 Harold G. Wolff Award.
Low Brain Magnesium in Migraine
Article first published online: 21 JUN 2005
Headache: The Journal of Head and Face Pain
Volume 29, Issue 7, pages 416–419, July 1989
How to Cite
Ramadan, N.M., Halvorson, H., Vande-Linde, A., Levine, S. R., Helpern, J.A. and Welch, K.M.A. (1989), Low Brain Magnesium in Migraine. Headache: The Journal of Head and Face Pain, 29: 416–419. doi: 10.1111/j.1526-4610.1989.hed2907416.x
Supported in part by NIH grant #NS23393 (to K.M.A.W.) and Henry Ford Hospital.
- Issue published online: 21 JUN 2005
- Article first published online: 21 JUN 2005
- Accepted for Publication: May 2, 1989
- Cited By
Brain magnesium was measured in migraine patients and control subjects using in vivo 31-Phosphorus Nuclear Magnetic Resonance Spectroscopy. pMg and pH were calculated from the chemical shifts between Pi, PCr and ATP signals. Magnesium levels were low during a migraine attack without changes in pH. We hypothesize that low brain magnesium is an important factor in the mechanism of the migraine attack.