Platelet Norepinephrine and Serotonin Balance in Migraine

Authors


  • This work was supported in part by NIH grant# NS23393.

Abstract

SYNOPSIS

Platelet serotonin (5 hydroxytryptamine, 5-HT) and norepinephrine (NE) were measured in common and classic migraine patients and healthy controls. Common migraine sufferers had high NE levels and a low 5-HT/NE ratio. Classic migraine patients had a high 5-HT level and a high 5-HT/NE ratio. The data suggest disparate NE and 5-HT metabolism between common and classic migraine.

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