Flunarizine Plasma Concentrations and Side Effects in Migraine Patients
Article first published online: 20 MAY 2005
Headache: The Journal of Head and Face Pain
Volume 30, Issue 6, pages 369–370, May 1990
How to Cite
Albani, F., Baldrati, A., Cortelli, P., Riva, R. and Baruzzi, A. (1990), Flunarizine Plasma Concentrations and Side Effects in Migraine Patients. Headache: The Journal of Head and Face Pain, 30: 369–370. doi: 10.1111/j.1526-4610.1990.hed3006369.x
- Issue published online: 20 MAY 2005
- Article first published online: 20 MAY 2005
- Accepted for Publication: February 22, 1990.
- Cited By
Flunarizine plasma concentrations and side effects were evaluated in migraine patients during a 3 month course of prophylactic treatment. Plasma concentrations did not correlate with daily dose (in mg/kg). Mean flunarizine levels were higher in patients showing sleepiness or sedation. Weight gain was independent of plasma concentrations. Future clinical trials of flunarizine should be supported by drug monitoring in order to clarify the relationship between plasma levels and drug effects.