Vascular Reactivity During Migraine Attacks: A Transcranial Doppler Study




We measured vascular reactivity - expressed i) as decrease in blood flow velocity (cm/sec) per vol% CO2decrease due to voluntary hyperventilation and ii) as increase of blood flow velocity during the first minuteafter resuming normal ventilation, per vol% CO2 increase - in the middle cerebral and basilar artery of 48migraineurs with attacks without aura, and 17 normal controls. We found no differences for bothdeterminants of vascular reactivity between migraineurs during and outside an attack, and betweenmigraineurs and healthy volunteers. We conclude that the vasomotor reactivity is normal during migraineattacks without aura.