From the Department of Neurology, University Hospital M de Valdecilla (UC), Santander, Spain.
Topiramate-Responsive Headache Due to Idiopathic Intracranial Hypertension in Behçet Syndrome
Article first published online: 7 MAY 2004
Headache: The Journal of Head and Face Pain
Volume 44, Issue 5, pages 436–437, June 2004
How to Cite
Palacio, E., Rodero, L. and Pascual, J. (2004), Topiramate-Responsive Headache Due to Idiopathic Intracranial Hypertension in Behçet Syndrome. Headache: The Journal of Head and Face Pain, 44: 436–437. doi: 10.1111/j.1526-4610.2004.04095.x
- Issue published online: 7 MAY 2004
- Article first published online: 7 MAY 2004
- Accepted for publication October 27, 2003.
- Behçet syndrome;
- carbonic anhydrase;
- intracranial hypertension;
A 14-year-old adolescent was seen with an 8-month history of almost daily incapacitating headaches due to idiopathic intracranial hypertension in Behçet syndrome. All his clinical signs and symptoms, including headache, resolved 2 to 4 weeks after topiramate was initiated. An effect on carbonic anhydrase isoenzymes II and IV, reducing cerebrospinal fluid production, could potentially explain the beneficial effect of topiramate in intracranial hypertension. Further studies are necessary, however, to confirm the significance of topiramate in this indication.