Coexistence of TACS and Trigeminal Neuralgia: Pathophysiological Conjectures

Authors

  • Massimo Leone MD,

  • Eliana Mea MD,

  • Sergio Genco MD,

  • Gennaro Bussone MD


  • From the Departments of Neurology and Headache, Istituto Nazionale Neurologico Carlo Besta, Milano, Italy (Leone, Mea, and Bussone); Department of Neurology, Clinica Neurologica I, Università di Bari, Italy (Genco).

Address all correspondence to Dr. Massimo Leone, Departments of Neurology and Headache, Istituto Nazionale Neurologico Carlo Besta, Milano, Italy.

Abstract

Background.—Trigeminal autonomic cephalgias (TACs) and trigeminal neuralgia are short-lasting unilateral primary headaches whose study is providing insights into craniofacial pain mechanisms. We report on 2 patients in whom trigeminal neuralgia coexists with the TACs paroxysmal hemicrania and SUNCT.

Conclusion.—Coexistence of trigeminal neuralgia with various TAC forms suggests a pathophysiological relationship between these short-lasting unilateral headaches.

Ancillary