From the Department of Neurology, Tokai University Tokyo Hospital, Tokyo, Japan.
A Case of Hypertrophic Pachymeningitis With Prolonged Headache, Attributable to Epstein–Barr Virus
Article first published online: 13 APR 2007
Headache: The Journal of Head and Face Pain
Volume 47, Issue 4, pages 620–622, April 2007
How to Cite
Okuma, H., Kobori, S., Shinohara, Y. and Takagi, S. (2007), A Case of Hypertrophic Pachymeningitis With Prolonged Headache, Attributable to Epstein–Barr Virus. Headache: The Journal of Head and Face Pain, 47: 620–622. doi: 10.1111/j.1526-4610.2007.00763_4.x
- Issue published online: 13 APR 2007
- Article first published online: 13 APR 2007
- Accepted for publication August 22, 2006.
- Epstein-Barr virus;
- hypertrophic pachymeningitis;
- prolonged headache
Hypertrophic pachymeningitis is a condition characterized by significant chronic inflammatory thickening of the cranial dura mater, frequently presenting with symptoms such as headache and cranial neuropathy. In this report, we describe a very rare case of hypertrophic pachymeningitis, considered to be attributable to Epstein–Barr virus (EBV), which was diagnosed in a patient who visited our hospital with a complaint of ongoing severe headaches. The diagnosis was based on positive specific serum EBV antibody titers, with VCA-IgM levels of less than 1:10, VCA-IgG levels of 1:160, and EBNA levels of 1:40, as well as on the results of magnetic resonance imaging of the head with contrast media.