Seizures With Prolonged EEG Abnormalities During an Attack of Migraine Without Aura


  • Giovanni Merlino MD,

  • Mariarosaria Valente MD,

  • Sebastiano D'Anna MD,

  • Gian Luigi Gigli MD

  • From the Department of Neurology, “Santa Maria della Misericordia” University Hospital, Udine, Italy (Drs. Merlino, Valente, and Gigli); DPMSC, University of Udine, Italy (Drs. Valente and Gigli); Neurology Unit, Portogruaro Hospital, Portogruaro, Italy (Dr. D'Anna).

Address all correspondence to Dr. Giovanni Merlino, Department of Neurology and Clinical Neurophysiology, Udine University Hospital, Udine, Italy, S. Maria della Misericordia Square, Udine 33100, Italy.


The term “migralepsy” indicates a particular condition in which seizures occur during a migraine attack. Several cases of seizures associated with migraine with aura and characterized by transient MRI abnormalities have been published. We report the case of a patient who presented 2 generalized seizures during an attack of migraine without aura and with a transient, diffuse, irregular, high voltage slow activity without clear epileptiform abnormalities in subsequent EEG recordings.