Hypnic Headache Responsive to Low-Dose Topiramate: A Case Report

Authors

  • Massimo Autunno MD,

  • Corrado Messina MD,

  • Anita Blandino MD,

  • Carmelo Rodolico MD


  • From the University of Messina – Department of Neurosciences, Psychiatry and Anaesthesiology, Messina, Italy.

  • Conflict of Interest: None

M. Autunno, Department of Neurosciences, Psychiatry and Anaesthesiology, University of Messina, via Consolare Valeria, Messina, Messina 98125, Italy.

Abstract

This is a clinical report of a 63-year-old woman, with a 3-year history of severe episodes of hypnic headache responding to low-doses of topiramate (25 mg at bedtime). Topiramate has been used at the dosage of 100 mg/day for hypnic headache prevention in one recent case report with benefit. This report confirms the efficacy of topiramate in hypnic headache even using low-dose regimen therapy.

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