Conflict of Interest: None
Correspondence and Clinical Notes†
Memantine and NMDA Antagonism for Chronic Migraine: A Potentially Novel Therapeutic Approach?
Article first published online: 8 JAN 2008
© 2008 the Authors
Headache: The Journal of Head and Face Pain
Volume 48, Issue 2, pages 284–286, February 2008
How to Cite
Spengos, K., Theleritis, C. and Paparrigopoulos, T. (2008), Memantine and NMDA Antagonism for Chronic Migraine: A Potentially Novel Therapeutic Approach?. Headache: The Journal of Head and Face Pain, 48: 284–286. doi: 10.1111/j.1526-4610.2007.01016.x
- Issue published online: 8 JAN 2008
- Article first published online: 8 JAN 2008
- Accepted for publication October 10, 2007.
- NMDA receptor;
- chronic migraine;
We present the case of a woman with chronic migraine who unexpectedly reported full remission of headache after memantine, an NMDA receptor antagonist, was administered for treating concomitant mild cognitive impairment. An underlying dose-dependent effect of memantine on headache symptoms in chronic daily headache and chronic migraine could be assumed.