Headache was first published in April 1961. Subscriptions cost $10 for 4 issues (a total of 201 pages). The journal expanded to 6 issues in 1976 with Volume 16 and grew again to 10 issues in 1986 with Volume 26. In 2006, the journal published 1597 pages with a further 220 editorial pages in supplementary material.
What follows is a facsimile of the first Table of Contents and the first Headache editorial.