Post-Traumatic Cluster Headache: From the Periphery to the Central Nervous System?


  • Conflict of Interest: None

G. Lambru, Headache Centre, Department of Neurology, University of Parma, c/o Ospedale Maggiore, via Gramsci 14, 43100 Parma, Italy.


A correlation between head trauma and cluster headache is believed to exist. We report a case of post-traumatic episodic cluster headache that fulfills the criteria of the International Classification of Headache Disorders, 2nd edition. The distinctive features of this case are: a close temporal relation between head trauma and headache onset; pain ipsilateral to the side of trauma; mild severity of trauma; episodic course well-responsive to low doses of verapamil. Given the close temporal relation between the 2 events, multiple hypotheses can be advanced about a possible role of head trauma in the pathogenesis of cluster headache.