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Coexisting Trigeminal Autonomic Cephalalgias and Hemicrania Continua

Authors

  • Matthew S. Robbins MD,

    1. From the Montefiore Headache Center, Saul R. Korey Department of Neurology, Bronx, NY, USA (M.S. Robbins, B.M. Grosberg, and R.B. Lipton), Department of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, NY, USA (R.B. Lipton).
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  • Brian M. Grosberg MD,

    1. From the Montefiore Headache Center, Saul R. Korey Department of Neurology, Bronx, NY, USA (M.S. Robbins, B.M. Grosberg, and R.B. Lipton), Department of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, NY, USA (R.B. Lipton).
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  • Richard B. Lipton MD

    1. From the Montefiore Headache Center, Saul R. Korey Department of Neurology, Bronx, NY, USA (M.S. Robbins, B.M. Grosberg, and R.B. Lipton), Department of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, NY, USA (R.B. Lipton).
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  • Disclosures: Dr. Robbins has nothing to disclose. Dr. Grosberg has received research support from Allergan, GSK, Merck, Neuralieve, Endo, Advanced Bionics, Proethics, Minster Research, Ltd, and Capnia. He has received honoraria from Merck and GSK, and is on the advisory board for Kowa Pharmaceutical. Dr. Lipton has received personal compensation for activities with Advanced Bionics, Allergan, AstraZeneca, Boehringer-Ingelheim, Bristol-Myers Squibb, Cierra, Endo, GSK, Minster Research, Ltd, Merck, Neuralieve, Novartis, and Ortho-McNeil as a consultant. He holds stock or stock options in Minster and Neuralieve. He has received research support from Allergan, Ortho-McNeil, Minster, Endo, GSK, Merck, Neuralieve, and ProEthics.

  • Conflict of Interest: None

M.S. Robbins, The Montefiore Headache Center, 1575 Blondell Avenue, Suite 225, Bronx, NY 10461, USA

Abstract

The trigeminal autonomic cephalalgias (TACs) and hemicrania continua (HC) share many clinical characteristics including unilateral pain and ipsilateral autonomic features. We report a patient with a history of migraine without aura who developed cluster headache and HC simultaneously. The distinctive clinical features and differential response profiles to various treatments indicates that they are distinct disorders. We then review previous reports of patients with coexisting TACs and HC and discuss the relationship between these families of primary headache disorders.

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