Conflict of Interest: None
Individual Differences in the Subjective Experience of Pain: New Insights Into Mechanisms and Models
Version of Record online: 4 OCT 2010
© 2010 American Headache Society
Headache: The Journal of Head and Face Pain
Volume 50, Issue 9, pages 1531–1535, October 2010
How to Cite
Coghill, R. C. (2010), Individual Differences in the Subjective Experience of Pain: New Insights Into Mechanisms and Models. Headache: The Journal of Head and Face Pain, 50: 1531–1535. doi: 10.1111/j.1526-4610.2010.01763.x
- Issue online: 4 OCT 2010
- Version of Record online: 4 OCT 2010
- Accepted for publication July 26, 2010.
- functional magnetic resonance imaging;
- anterior insular cortex
Individual differences in pain sensitivity have long remained a perplexing and challenging clinical problem. How can one individual have a sensory experience that is vastly different than that of another, even when they have received similar sensory input? Developing an understanding of such differences and the mechanisms that support them has progressed substantially as psychophysical findings are integrated with measures of brain activation provided by functional brain imaging techniques. Continued delineation of these mechanisms will contribute substantially to the development of combined psychophysical/psychological models that can be used to optimize pain treatment on an individual-by-individual basis.