Atrophy of Corrugator Supercilii Muscle in a Patient Induced by the Onabotulinum Toxin Injection

Authors

  • Chong-hao Zhao MD, PhD,

    Corresponding author
    1. From the California Headache and Pain Center, Burbank, CA, USA (C.-H. Zhao); Department of Neurology, Cleveland Clinic Foundation, Cleveland, OH, USA (M. Stillman).
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  • Mark Stillman MD

    1. From the California Headache and Pain Center, Burbank, CA, USA (C.-H. Zhao); Department of Neurology, Cleveland Clinic Foundation, Cleveland, OH, USA (M. Stillman).
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  • Conflict of Interest: Chonghao Zhao: Principal investigator (in a group) for CD-PROBE (Cervical Dystonia Patient Registry for Observation of BOTOX Efficacy) A Multicenter, Observational Study of Repeated OnabotulinumtoxinA Injections in Cervical Dystonia.

  • Financial support: None available.

C.-H. Zhao, California Headache and Pain Center, 201 South Buena Vista Street, Suite 238, Burbank, CA 91505, USA, email: Drzhao@chpci.com

Abstract

Onabotulinum toxin has been used to treat a variety of headaches. We report a case of a 29-year-old woman who developed temporary and reversible atrophy of corrugator supercilii muscle after onabotulinum toxin (Botox, Allergan, Irvine, CA, USA) injection. To our best knowledge this has not been described in the literature before.

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