Late Cytotoxic Edema in 2 Children With Hemiplegia: Hemiplegic Migraine or Stroke?

Authors

  • Sita Kedia MD,

    Corresponding author
    1. From the Section of Child Neurology, University of Colorado School of Medicine, Aurora, CO, USA (S. Kedia, J. Armstrong-Wells, and T.J. Bernard); Section of Radiology, University of Colorado School of Medicine, Aurora, CO, USA (N. Stence); Section of Hematology/Oncology, University of Colorado School of Medicine, Aurora, CO, USA (M. Manco-Johnson); Children's Hospital Colorado Department of Pediatrics, University of Colorado School of Medicine, Aurora, CO, USA (S. Kedia, N. Stence, M. Manco-Johnson, J. Armstrong-Wells, and T.J. Bernard).
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  • Nicholas Stence MD,

    1. From the Section of Child Neurology, University of Colorado School of Medicine, Aurora, CO, USA (S. Kedia, J. Armstrong-Wells, and T.J. Bernard); Section of Radiology, University of Colorado School of Medicine, Aurora, CO, USA (N. Stence); Section of Hematology/Oncology, University of Colorado School of Medicine, Aurora, CO, USA (M. Manco-Johnson); Children's Hospital Colorado Department of Pediatrics, University of Colorado School of Medicine, Aurora, CO, USA (S. Kedia, N. Stence, M. Manco-Johnson, J. Armstrong-Wells, and T.J. Bernard).
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  • Marilyn Manco-Johnson MD,

    1. From the Section of Child Neurology, University of Colorado School of Medicine, Aurora, CO, USA (S. Kedia, J. Armstrong-Wells, and T.J. Bernard); Section of Radiology, University of Colorado School of Medicine, Aurora, CO, USA (N. Stence); Section of Hematology/Oncology, University of Colorado School of Medicine, Aurora, CO, USA (M. Manco-Johnson); Children's Hospital Colorado Department of Pediatrics, University of Colorado School of Medicine, Aurora, CO, USA (S. Kedia, N. Stence, M. Manco-Johnson, J. Armstrong-Wells, and T.J. Bernard).
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  • Jennifer Armstrong-Wells MD, MPH,

    1. From the Section of Child Neurology, University of Colorado School of Medicine, Aurora, CO, USA (S. Kedia, J. Armstrong-Wells, and T.J. Bernard); Section of Radiology, University of Colorado School of Medicine, Aurora, CO, USA (N. Stence); Section of Hematology/Oncology, University of Colorado School of Medicine, Aurora, CO, USA (M. Manco-Johnson); Children's Hospital Colorado Department of Pediatrics, University of Colorado School of Medicine, Aurora, CO, USA (S. Kedia, N. Stence, M. Manco-Johnson, J. Armstrong-Wells, and T.J. Bernard).
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  • Timothy J. Bernard MD

    1. From the Section of Child Neurology, University of Colorado School of Medicine, Aurora, CO, USA (S. Kedia, J. Armstrong-Wells, and T.J. Bernard); Section of Radiology, University of Colorado School of Medicine, Aurora, CO, USA (N. Stence); Section of Hematology/Oncology, University of Colorado School of Medicine, Aurora, CO, USA (M. Manco-Johnson); Children's Hospital Colorado Department of Pediatrics, University of Colorado School of Medicine, Aurora, CO, USA (S. Kedia, N. Stence, M. Manco-Johnson, J. Armstrong-Wells, and T.J. Bernard).
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  • Funding: SK research supported in part by Health Resources and Service Administration (HRSA) Faculty Development Research Fellowship.

  • Conflict of Interest: The authors report no conflict of interest.

S. Kedia, Children's Hospital Colorado, 13123 East 16th Ave. B155, Aurora, CO 80045, USA.

Abstract

Hemiplegic migraine (HM) is a rare variant of migraine with aura, characterized by migrainous headache and fully reversible motor deficit within 24 hours. Both sporadic and familial forms of HMs are genetically heterogenous with little information on neuroimaging during and after acute attacks. We report 2 cases of children with presumed HM and late cytotoxic edema.

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