Conflict of Interest: None
New Daily Persistent Headache
Article first published online: 27 APR 2012
© 2012 American Headache Society
Headache: The Journal of Head and Face Pain
Special Issue: Proceedings of the Inaugural Southern Headache Society Meeting
Volume 52, Issue Supplement s1, pages 40–44, May 2012
How to Cite
Evans, R. W. (2012), New Daily Persistent Headache. Headache: The Journal of Head and Face Pain, 52: 40–44. doi: 10.1111/j.1526-4610.2012.02135.x
- Issue published online: 27 APR 2012
- Article first published online: 27 APR 2012
- Accepted for publication February 19, 2012.
- new daily persistent headache;
- chronic daily headache;
- chronic migraine
Primary new daily persistent headache is a rare disorder of children and adults defined by the onset of daily and unremitting headaches within 3 days of onset lasting 4 hours or more daily. There may be a link between a preceding flu-like or upper respiratory infection in about 15%, a stressful life event in 10%, or extracranial surgery in 10%. Migraine symptoms may be present in over 50%. The headache is generalized in most but may be unilateral in 11% and may be localized to any head region. The diagnosis is one of exclusion as many secondary etiologies can cause similar headaches. The pathophysiology of the primary type is unknown. There are no prospective placebo controlled trials of preventive treatment so prevention is empiric using the same medications for the phenotype of chronic migraine or tension-type headache. Most patients have persistent headaches, although about 15% will remit, and 8% will have a relapsing-remitting type.