These authors contributed equally to this work.
The Study of Time Perception in Migraineurs
Version of Record online: 23 JUL 2012
© 2012 American Headache Society
Headache: The Journal of Head and Face Pain
Volume 52, Issue 10, pages 1483–1498, November/December 2012
How to Cite
Zhang, J., Wang, G., Jiang, Y., Dong, W., Tian, Y. and Wang, K. (2012), The Study of Time Perception in Migraineurs. Headache: The Journal of Head and Face Pain, 52: 1483–1498. doi: 10.1111/j.1526-4610.2012.02222.x
Conflict of Interest: None.
- Issue online: 15 NOV 2012
- Version of Record online: 23 JUL 2012
- Accepted for publication May 22, 2012.
- time perception;
- motor timing;
- basal ganglia
Objective.— The study aimed to explore the impairment of time perception in migraineurs.
Background.— Headache is the most common pain syndrome in middle-aged adults, and migraine is highly prevalent and severely disabling. Although the mechanisms of and the therapies for migraines have long been explored, less is known about the functional impairments associated with them, especially the impairment in time perception, that is, the ability to estimate the passage of time.
Methods.— In this study, we used a temporal reproduction task to assess the estimation of the duration of visual stimulus in 27 migraine patients. The stimulus was delivered at different intervals over the milliseconds and seconds range.
Results.— In the setting of an interstimulus interval for 1 second and an interstimulus interval for 5 seconds in the 600-millisecond-duration reproduction task, the migraineurs showed impairment in time perception, and in that they significantly overestimated the duration, as compared with the healthy subjects. When compared with the healthy controls for the 3-second and 5-second duration reproduction task, migraineurs in the setting of an interstimulus interval for 1 second and an interstimulus interval for 5 seconds did not show impairment in time perception.
Conclusions.— This study indicates that not only is time perception impaired in migraineurs, but that this impairment is exhibited for durations in the milliseconds range, and not the seconds range.