Now working as a Clinical Psychologist in the Peel Community Mental Health Service, Mandurah, Western Australia, Australia.
An Exploratory Study of Changes in Salivary Cortisol, Depression, and Pain Intensity After Treatment for Chronic Pain
Article first published online: 20 AUG 2007
© American Academy of Pain Medicine
Volume 9, Issue 6, pages 752–758, September 2008
How to Cite
Evans, K. D., Douglas, B., Bruce, N. and Drummond, P. D. (2008), An Exploratory Study of Changes in Salivary Cortisol, Depression, and Pain Intensity After Treatment for Chronic Pain. Pain Medicine, 9: 752–758. doi: 10.1111/j.1526-4637.2006.00285.x
- Issue published online: 20 AUG 2008
- Article first published online: 20 AUG 2007
- Chronic Pain;
Objective. To investigate the relationship between cortisol levels, pain intensity, and negative mood in chronic pain patients participating in a multidisciplinary pain management program.
Patients. Eighteen chronic pain patients collected saliva samples over several days both directly before and after attending a 4-week multidisciplinary pain management program.
Outcome Measures. Saliva samples were assayed for their cortisol concentration. Participants also completed self-report measures of pain intensity and depression.
Results. Usual pain intensity and waking cortisol levels changed in parallel following treatment, as did changes in depression and cortisol levels late in the morning and in the evening. Depression did not mediate the association between cortisol and usual pain intensity; neither did pain intensity moderate the association between cortisol and depression.
Conclusions. Changes in cortisol secretion may provide a useful biological marker of treatment outcome in chronic pain patients after their participation in a multidisciplinary pain management program.