Treatable Partial Epilepsy and Unilateral Opercular Neuronal Migration Disorder
Article first published online: 3 AUG 2005
Volume 34, Issue 4, pages 604–608, July 1993
How to Cite
Ambrosetto, G. (1993), Treatable Partial Epilepsy and Unilateral Opercular Neuronal Migration Disorder. Epilepsia, 34: 604–608. doi: 10.1111/j.1528-1157.1993.tb00435.x
- Issue published online: 3 AUG 2005
- Article first published online: 3 AUG 2005
- Received March 1993; revision accepted April 1993.
- Benign epilepsy;
- Rolandic operculum;
- Cerebral cortex
Summary: Five patients with treatable partial epilepsy and unilateral opercular neuronal migration disorder (NMD) are reported. Outcome was considered favorable when seizure control was prompt and complete with appropriate antiepileptic drug (AED) therapy, and when there was no relapse after AED discontinuation. Minor cortical sensorimotor defects were noted in 4 patients. All had normal mental status. No epileptic discharges were observed in the EEG of 4 patients, but rolandic spikes were observed in 1. The electroclinical and evolutive features suggested partial idiopathic epilepsy in 2 patients. Cases with focal neuronal migration disorders and favorable epilepsy outcome are probably more common than has been reported previously. The extent and location of the underlying microscopic lesions associated with the radiologically detectable cortical dysplasia may influence clinical outcome.