Presented in part at the annual meeting of The American Epilepsy Society in Philadelphia, December 10, 1991 and published in abstract form in Epilepsia 1991;32(suppl 1):64.
Chronic Intractable Epilepsy as the Only Symptom of Primary Brain Tumor
Article first published online: 3 AUG 2005
Volume 34, Issue 6, pages 1038–1043, November 1993
How to Cite
Morris, H. H., Estes, M. L., Gilmore, R., Van Ness, P. C., Barnett, G. H. and Turnbull, J. (1993), Chronic Intractable Epilepsy as the Only Symptom of Primary Brain Tumor. Epilepsia, 34: 1038–1043. doi: 10.1111/j.1528-1157.1993.tb02131.x
- Issue published online: 3 AUG 2005
- Article first published online: 3 AUG 2005
- Received August 1992; revision accepted October 1992.
- Brain tumor;
- Neurologic manifestations
We identified 39 patients with chronic epilepsy (seizures ≥2 years) proven to have primary brain tumors. These cases represent ∼12% of the surgery cases for epilepsy in the same period. Mean age of seizure onset was 13.2 years: mean duration before operation was 10.5 years. Thirty-eight of 39 had normal neurologic examination. Twenty-six tumors were temporal, 7 were frontal, 4 were parietal, and 2 were occipital. Nine of 26 (34.6%) of the temporal group had contralateral interictal EEG spikes. Pathology was 15 ganglioglioma, 13 low-grade astrocytoma, 4 oligodendroglioma, 2 low-grade mixed glioma, 1 pleomorphic xanthoastrocytoma, 2 dysembryoplastic neuroepithelial tumor, and 1 ependymoma. Postoperative seizure frequency (minimum follow-up 6 months) ranged from 15 to 16 seizure-free or auras only in patients with temporal tumors and total gross tumor removal (mean follow-up 28 months) to 0 of 6 seizure-free in patients with extratemporal tumors who underwent subtotal resections or biopsy.