Incidence of Acute Symptomatic Seizures in Rochester, Minnesota, 1935-1984
Article first published online: 3 AUG 2005
Volume 36, Issue 4, pages 327–333, April 1995
How to Cite
Annegers, J. F., Hauser, W. A., Lee, J. R.-J. and Rocca, W. A. (1995), Incidence of Acute Symptomatic Seizures in Rochester, Minnesota, 1935-1984. Epilepsia, 36: 327–333. doi: 10.1111/j.1528-1157.1995.tb01005.x
- Issue published online: 3 AUG 2005
- Article first published online: 3 AUG 2005
- Received March 14, 1994; revision accepted June 29, 1994.
- Traumatic brain injury;
- Cerebrovascular disease;
- Drug withdrawal;
- CNS infection;
- Rochester, Minnesota
Summary We determined the incidence of seizures due to acute CNS insults for residents of Rochester, Minnesota, U.S.A., from 1935 though 1984. The age-adjusted incidence rates for 1955–1984, the period of most complete case ascertainment, was 39.0/100,000 person-years (United States 1970 population as standard). The age-adjusted incidence was considerably higher in men: 52.0 as compared with 29.5 in women. The 3.6% risk of experiencing an acute symptomatic seizure in an 80-year lifespan approaches that of developing epilepsy. The major causes of acute symptomatic seizures were traumatic brain injury, cerebrovascular disease, drug withdrawal, and CNS infections. Each type of acute symptomatic seizure has age, gender, and time period patterns that reflect the occurrence of the underlying cause.