Dr. Rabinowicz's present address is Instituto de Investigaciones Neurologicas Raul Carrea (FLENI), Buenos Aires, Argentina.
Neuron-Specific Enolase Is Increased After Single Seizures During Inpatient Video/EEG Monitoring
Article first published online: 3 AUG 2005
Volume 37, Issue 2, pages 122–125, February 1996
How to Cite
Rabinowicz, A. L., Correale, J., Boutros, R. B., Couldwell, W. T., Henderson, C. W. and DeGiorgio, C. M. (1996), Neuron-Specific Enolase Is Increased After Single Seizures During Inpatient Video/EEG Monitoring. Epilepsia, 37: 122–125. doi: 10.1111/j.1528-1157.1996.tb00002.x
- Issue published online: 3 AUG 2005
- Article first published online: 3 AUG 2005
- Received May 22, 1995; revision accepted October 9, 1995.
- specific enolase;
- electroencephalograpic monitoring;
Neuron-specific enolase (NSE) is a marker of brain injury after acute neurologic insults. We report changes in serum NSE (s-NSE) in 25 patients (15 with epilepsy and 10 patients with nonepileptic events) during continuous inpatient video/EEG monitoring. s-NSE was significantly increased as compared with baseline and normal controls after the first ictal event in the epileptic group, especially in patients with secondarily generalized tonic-clonic seizures (p = 0.01), but s-NSE was not increased in patients with nonepileptic events. These preliminary data indicate that s-NSE may be increased after complex partial seizures-and generalized tonic-clonic seizures (GTCS).