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REFERENCES

  • 1
    Tüngel C. Ein Fall von Neubildung grauer Hirnsubstanz. Virchous Arch Pathol Anat 1859:16:1668.
  • 2
    Virchow R. Zur Pathologischen Anatomie des Gehirns: II. Heterotopie des grauen Hirnsubstanz. Arch Pathol Anat 1867;38:13842.
  • 3
    Alzheimer A. Die Gruppierung der Epilepsie. Allg Z Psychiatri 1907;64:41821.
  • 4
    Aicardi J. The place of neuronal migration abnormalities in child neurology. Can J Neurol Sci 1994;21:18593.
  • 5
    Barth PG. Disorders of neuronal migration. Can J Neurol Sci 1987;14:116.
  • 6
    Barkovitch AJ, Gressens P, Evrard P. Formation, maturation and disorders of brain neocortex. Am J Neuroradiol 1992;13:42346.
  • 7
    Harding BN, Duchen LW. Malformations. In: AdamsJH, ed. Greenfiled's neuropathology. New York : Oxford University Press, 1992:521638.
  • 8
    Norman MG. Malformations of the brain. J Neuropathol Exp Neurol 1996;55:13343.
  • 9
    Barkovitch AJ, Kuzniecky RI, Jackson GD, Becker LE, Evrard P. A classification scheme for malformations of cortical development. Neuropediatrics 1996;27:5963.
  • 10
    Kuzniecky RI, Jackson GD. Developmental disorders. In: EngelJJr, PedleyTA, eds. Epilepsy: a comprehensive textbook. Philadelphia : Lippincott-Raven Publishers, 1997:251732.
  • 11
    Mischel PS, Nguyen LP, Vinters HV. Cerebral cortical dysplasia associated with pediatric epilepsy: review of neuropathological features and proposal for a grading system. J Neuropathol Exp Neurol 1995;54:13753.
  • 12
    Robain O. Introduction to the pathology of cerebral cortical dysplasia. In: GuerriniR, AndermannE, CanapicchiR, et al., eds. Dysplasias of the cerebral cortex and epilepsy. Philadelphia : Lippincott-Raven, 1996:19.
  • 13
    Sarnat HB. Cerebral dysplasias as expressions of altered maturational processes. Can J Neurol Sci 1991;18:196204.
  • 14
    Rorke LB. A perspective: the role of disordered genetic control of neurogenesis in the pathogenesis of migration disorders. J Neuropathol Exp Neurol 1994;53:10517.
  • 15
    Barkovitch AJ, Guerrini R, Battaglia G, et al. Band heterotopia: correlation of outcome with magnetic resonance imaging parameters. Ann Neurol 1994;36:60917.
  • 16
    Müller RA, Behen ME, Muzik O, et al. Task-related activations in heterotopic brain malformations. Neuroreport 1998;9:252733.
  • 17
    Taylor DC, Falconer MA, Bruton CJ, Corsellis JAN. Focal dysplasia of the cerebral cortex in epilepsy. J Neurol Neurosurg Psychiatry 1971;34:36987.
  • 18
    Duong T, De Rosa MJ, Poukens V, Vinters HV, Fisher RS. Neuronal cytoskeletal abnormalities in human cerebral cortical dysplasia. Acta Neuropathol 1994;87:493503.
  • 19
    DeRosa MJ, Secor DL, Barsom M, Fisher RS, Vinters HV. Neuropathologic findings in surgically treated hemimegalencephaly: immunohistochemical, morphometric, and ultrastructural study. Acta Neuropathol 1992;84:25060.
  • 20
    Robain O, Chiron C, Dulac O. Electron microscopy and Golgi analysis in a case of hemimegalencephaly. Acta Neuropathol 1989;77:6646.
  • 21
    Reiner O, Carrozzo R, Shen Y, et al. Isolation of a Miller-Dieker lissencephaly gene containing G protein b-subunit-like repeats. Nature 1993;364:71721.
  • 22
    des Portes V, Pinard J-M, Billuart P, et al. Identification of a novel CNS gene required for neuronal migration and involved in X-linked subcortical laminar heterotopia and lissencephaly syndrome. Cell 1998;92:5161.
  • 23
    Gleeson JG, Allen KM, Fox JW, et al. doublecortin: A brain-specific gene mutated in X-linked lissencephaly and double cortex syndrome, encodes a putative signaling protein. Cell 1998;92:6372.
  • 24
    Eksioglu YZ, Scheffer IE, Cardenas P, et al. Periventricular heterotopia: an X-linked dominant epilepsy locus causing aberrant cerebral cortical development. Neuron 1996;16:7787.
  • 25
    Palmini A, Andermann E, Andermann F. Prenatal events and genetic factors in epileptic patients with neuronal migration disorders. Epilepsia 1994;35:96573.
  • 26
    Lee KS, Schottler F. Collins JL, et al. A genetic model of human neocortical heterotopia associated with seizures. J Neurosci 1997;17:623642.
  • 27
    Schotter F, Couture D, Rao A, Kahn H, Lee KS. Subcortical connections of normotopic and heterotopic neurons in sensory and motor cortices of th. tish mutant rat. J Comp Neurol 1998;25:2942.
  • 28
    Lee KS, Collins JL, Anzivino MJ, Frankel EA, Schottler F. Heterotopic neurogenesis in a rat with cortical heterotopia. J Neurosci 1998;18:936575.
  • 29
    Collins JL, Lee KS. Calretinin immunoreactivity in the cortex of the developing Tish neurological mutant [Abstract]. Soc Neurosci Abstr 1997;23:1696.
  • 30
    Falconer D. Two new mutants, “trembler” and “reeler,” with neurological actions in the house mouse. J Genet 1951;50:192201.
  • 31
    Caviness VS Jr. Patterns of cell and fiber distribution in the neocortex of the reeler mutant mice. J Comp Neurol 1976;170:43548.
  • 32
    Caviness VS Jr, Sidman RL. Time of origin of corresponding cell classes in the cerebral cortex of normal and reeler mutant mice: an autoradiographic analysis. J Comp Neurol 1973;148:14151.
  • 33
    Chae T, Kwon YT, Bronson R, Dikkes P, Li E, Tsai L-H. Mice lacking p35, a neuronal specific activator of cdk5, display cortical lamination defects, seizures, and adult lethality. Neuron 1997;18:2942.
  • 34
    Pearlman AL, Faust PL, Hatten ME, Brunstrom JE. New directions for neuronal migration. Curr Opin Neurobiol 1998;8:4554.
  • 35
    Goffinet AM. The cerebral cortex of the reeler mouse embryo: an electron microscopic analysis. Anat Embryol 1980;159:199210.
  • 36
    Kwon YT, Tsai LH. A novel disruption of cortical development i. p35(-/-) mice distinct from reeler. J Comp Neurol 1998;395:51022.
  • 37
    Gleeson JG, Walsh CA. New genetic insights into cerebral cortical development. In: GalaburdaAM, ChristenY, eds. Normal and abnormal development of the cortex. Berlin : Springer-Verlag, 1997:14563.
  • 38
    Amano S, Ihara N, Uemura S, et al. Development of novel rat mutant with spontaneous limbic-like seizures. Am J Pathol 1996;149:32936.
  • 39
    Amano S, Yokoyama M, Torii R, Fukuoka J, Ihara N, Hazama F. High performance seizure-monitoring system using a vibration sensor and videotape recording: behavioral analysis of genetically epileptic rats. Lab Anim Sci 1997;47:31720.
  • 40
    Miller MW. Effects of alcohol on generation and migration of cerebral cortex neurons. Science 1986;233:130811.
  • 41
    Miller MW. Effect of prenatal exposure to alcohol on the distribution and time of origin of corticospinal neurons in the rat. J Comp Neurol 1987;257:37282.
  • 42
    Gressens P, Lammens M, Picard JJ, Evrard P. Ethanol-induced disturbances of gliogenesis and neurogenesis in the developing murine brain: an in vitro and in vivo immunohistochemical and ultrastructural study. Alcohol Alcohol 1992;27:21926.
  • 43
    Gressens P, Kosofsky BE, Evrard P. Cocaine-induced disturbances of corticogenesis in the developing murine brain. Neurosci Lett 1992;140:1136.
  • 44
    Jones L, Fisher I, Levitt P. Non-uniform alteration of dendritic development in the cerebral cortex following prenatal cocaine exposure. Cerebr Cortex 1996;6:43145.
  • 45
    Miller MW. Effects of prenatal exposure to ethanol on callosal projection neurons in rat somatosensory cortex. Brain Res 1997;766:1218.
  • 46
    Miller MW, Chiaia NL, Rhoades RW. Intracellular recording and injection study of corticospinal neurons in the rat somatosensory cortex: effect of prenatal exposure to ethanol. J Comp Neurol 1990;297:91105.
  • 47
    Cattaneo E, Reinach B, Caputi A, Cattabeni F, Di Luca M. Selective in vitro blockade of neuroepithelial cells proliferation by methylazoxymethanol acetate, a molecule capable of inducing long lasting functional impairements. J Neurosci Res 1995;41:6407.
  • 48
    Hicks SP, D'Amato CJ, Lowe MJ. The development of the mammalian nervous system: I. Malformation of the brain, especially the cerebral cortex, induced in rats by radiation. II. Some mechanisms of the malformations of the cortex. J Comp Neurol 1959;113:43569.
  • 49
    Zhang LL, Collier PA, Ashwell KWS. Mechanisms in the induction of neuronal heterotopiae following prenatal cytotoxic brain damage. Neurotoxicol Teratol 1995;17:297311.
  • 50
    Roper SN, Abraham LA, Streit WJ. Exposure to in utero irradiation produces disruption of radial glia in rats. Dev Neurosci 1997;19:5218.
  • 51
    Dambska M, Haddad R, Kozlowski PB, Lee MH, Shek J. Telencephalic cytoarchitectonics in the brains of rats with graded degrees of micrencephaly. Acta Neuropathol 1982;58:2039.
  • 52
    Johnston MV, Coyle JT. Histological and neurochemical effects of fetal treatment with methylazoxymethanol on rat neocortex in adulthood. Brain Res 1979;170:13555.
  • 53
    Jensen KF, Altman J. The contribution of late generated neurons to the callosal projection in the rat: a study with prenatal x-irradiation. J Comp Neurol 1982;209:11322.
  • 54
    Ferrer I, Xumetra A, Santamaria J. Cerebral malformation induced by prenatal X-irradiation: an autoradiographic and Golgi study. J Anat 1984;138:8193.
  • 55
    Collier PA, Ashwell KWS. Distribution of neuronal heterotopias following prenatal exposure to methylazoxymethanol. Neurotoxicol Teratol 1993;15:43944.
  • 56
    Chevassus-au-Louis N, Rafiki A, Jorquera I, Ben-Ari Y, Represa A. Neocortex in the hippocampus: morpho-functional analysis of CA1 heterotopias after prenatal treatment with methylazoxymethanol in rats. J Comp Neurol 1998;394:52036.
  • 57
    Ferrer I, Fabregues I, Palacios G. An autoradiographic study of methylazoxymethanol acetate-induced cortical malformation. Acta Neuropathol 1982;57:3135.
  • 58
    Ferrer I, Alcantara S, Zujer MI, Cinos C. Structure and pathogenesis of cortical nodules induced by prenatal x-irradiation in the rat. Acta Neuropathol 1993;85:20512.
  • 59
    Dvorak K, Feit J. Migration of neuroblasts through partial necrosis of the cerebral cortex in newborn rats: contribution to the problems of morphological development and developmental period of cerebral microgyria. Acta Neuropathol 1977;38:20312.
  • 60
    Dvorak K, Feit J, Jurankova Z. Experimentally induced focal microgyria and status verucosus deformis in rats: pathogenesis and interrelation histological and autoradiographical study. Acta Neuropathol 1978;44:1219.
  • 61
    MacBride M. Temper T. Pathogenesis of four-layered microgyric cortex in man. Acta Neuropathol 1982;57:938.
  • 62
    Rosen GD, Sherman GF, Galaburda AM. Birthdates of neurons in induced microgyria. Brain Res 1996;727:718.
  • 63
    Rosen GD, Press DM, Sherman GF, Galaburda AM. The development of induced cerebrocortical microgyria in the rat. J Neuropathol Exp Neurol 1992;51:60111.
  • 64
    Innocenti GM, Berbel P. Analysis of an experimental cortical network: ii) Connections of visual areas 17 and 18 after neonatal injections of ibotenic acid. J Neurol Transm 1991;2:2954.
  • 65
    Marret S, Mukendi R, Gadisseux J-F, Gressens P, Evrard P. Effect of ibotenate on brain development: an excitotoxic mouse model of microgyria and posthypoxic-like lesions. J Neuropathol Exp Neurol 1995;54:35870.
  • 66
    Barkovitch AJ, Kjos BO. Gray matter heterotopias: MR characteristics and correlation with developmental and neurological manifestations. Radiology 1992;182:4939.
  • 67
    Palmini A, Andermann F, Olivier A, Tampieri D, Robitaille Y, Andermann E. Focal neuronal migration disorders and intractable epilepsy: a study of 30 patients. Ann Neurol 1991;30:7419.
  • 68
    Smith AS, Weinstein MA, Quencer RM, et al. Association of heterotopic gray matter with epilepsy. Radiology 1988;168:1958.
  • 69
    Raymond AA, Fish DR, Sisodiya SM. Abnormalities of gyration, heterotopias, tuberous sclerosis, focal cortical dysplasia, micro-dysgenesis, dysembryoblastic neuroepithelial tumour and dysgenesis of the archicortex in epilepsy: clinical, EEG and neuroimaging features in 100 adult patients. Brain 1995;188:62960.
  • 70
    Prayson RA, Estes ML. Cortical dysplasia: a histopathological study of 52 cases of partial lobectomy in patients with epilepsy. Hum Pathol 1995;26:493500.
  • 71
    Meencke HJ, Veith G. Migration disturbances in epilepsy. In: EngelJJr, WasterlainC, CavalheiroEA HeinemannU, eds. Molecular and cellular neurobiology of epilepsy. Amsterdam : Elsevier Science Publisher, 1992:3140.
  • 72
    Gelot A, Billette de Villemeur T, Bordarier C, Ruchoux MM, Moraine C, Ponsot G. Developmental aspects of type II lissencephaly: comparative study of dysplastic lesions in fetal and postnatal brains. Acta Neuropathol 1995;89:7284.
  • 73
    Granata T, Battaglia G, D'Incerti L, et al. Schizencephaly: neuroradiologic and epileptogenic finfings. Epilepsia 1996;37:118593.
  • 74
    Jellinger K. Neuropathological aspects of infantile spasms. Brain Dev 1987;9:34957.
  • 75
    Dulac O. Infantile spasms and West syndrome. In: EngelJJr, PedleyTA, eds. Epilepsy, a comprehensive textbook. Philadelphia : Lippincott-Raven, 1997:227783.
  • 76
    Dubeau F, Tampieri D, Lee N, et al. Periventricular and subcortical nodular heterotopia: a study of 33 patients. Brain 1995;118:127387.
  • 77
    Battaglia G, Granata T, Farina L, D'Incerti L, Franceschetti S, Avanzini G. Periventricular nodular heterotopia: epileptogenic findings. Epilepsia 1997;38:117382.
  • 78
    Raymond AA, Fish DR, Stevens JM, Sisodiya SM, Alsanjari N, Shorvon SD. Subependymal heterotopia: a distinct neuronal migration disorder associated with epilepsy. J Neurol Neurosurg Psychiatry 1994;57:1195202.
  • 79
    Germano IM, Zhang YF, Sperber EF, Moshé SL. Neuronal migration disorders increase susceptibility to hyperthermia induced seizures in developing rats. Epilepsia 1996;37:90210.
  • 80
    Germano IM, Sperber EF. Transplacentally induced neuronal migration disorders: an animal model for the study of the epilepsies. J Neurosci Res 1998;15:47388.
  • 81
    De Feo MR, Mecarelli O, Ricci GF. Seizure susceptibility in immature rats with microencephaly induced by prenatal exposure to methylazoxymethanol acetate. Pharmacol Res 1995;31:10914.
  • 82
    Baraban SC, Schwartzkroin PA. Flurothyl seizure susceptibility in rats following prenatal methylazoxymethanol treatment. Epilepsy Res 1996;23:18994.
  • 83
    Germano IM, Sperber EF. Increased seizure susceptibility in adult rats with neuronal migration disorders. Brain Res 1997;777:21922.
  • 84
    Komuro H, Rakic P. Modulation of neuronal migration by NMDA receptors. Science 1995;260:957.
  • 85
    Hattori M, Adachi H, Tsujimoto M, Arai H, Inoue K. Miller-Dicker lissencephaly gene encodes a subunit of brain platelet-activating factor acetylhydrolase. Nature [erratum in Nature 1994;4:370, 391] 1994;370:2168.
  • 86
    Bix GJ, Clark GD. Platelet-activating factor receptor stimulation disrupts neuronal migration in vitro. J Neurosci 1998;18:30718.
  • 87
    Bito H, Nakamura M, Honda Z, et al. Platelet-activating factor (PAF) receptor in rat brain: PAF mobilizes intracellular Ca2+ in hippocampal neurons. Neuron 1993;9:28594.
  • 88
    Walsh CA. Neuronal identity, neuronal migration, and epileptic disorders of the cerebral cortex. In: SchwartzkroinPA, MoshéSL, NoebelsJL SwannJW, eds. Brain development and epilepsy. New York : Oxford University Press, 1995:12243.
  • 89
    Lee N, Radtke RA, Gray L. Neuronal migration disorders: positron emission tomography correlations. Ann Neurol 1994;35:2907.
  • 90
    Chugani HT, Shields WD, Shewmon DA, Olson DM, Phelps ME, Peacock WJ. Infantile spasms. I. PET identifies focal cortical dysplasia in cryptogenic cases for surgical treatment. Ann Neurol 1990;27:40613.
  • 91
    Chiron C, Dulac O, Bulteau C. Study of regional blood flow in West syndrome. Epilepsia 1993;34:70715.
  • 92
    Palmini A, Gambardella A, Andermann F, et al. Intrinsic epileptogenicity of human dysplastic cortex as suggested by corticography and surgical results. Ann Neurol 1995;37:46787.
  • 93
    Morrell F, Whisler WW, Hoeppner TJ, et al. Electrophysiology of heterotopic gray matter in the “double cortex syndrome” [Abstract]. Epilepsia 1997;33(suppl 3):76.
  • 94
    Raymond AA, Fish DR. EEG features of focal malformations of cortical development. J Clin Neurophysiol 1998;13:495506.
  • 95
    Mattia D, Olivier A, Avoli M. Seizure-like discharges recorded in human dysplastic neocortex maintained in vitro. Neurology 1995;45:13915.
  • 96
    Spreafico R, Battaglia G, Arcelli P, et al. Cortical dysplasia: art immunohistochemical study of three patients. Neurology 1998;50:2736.
  • 97
    Ferrer I, Pineda M, Tallada M, et al. Abnormal local-circuit neurons in epilepsia partialis continua associated with focal cortical dysplasia. Acta Neuropathol 1992;83:64752.
  • 98
    Ferrer I, Oliver B, Russi A, Casas R, Rivera R. Parvalbumin and calbindin-D28K immunocytochemistry in human neocortical epileptic foci. J Neurol Sci 1994;123:1825.
  • 99
    Spreafico R, Pasquier B, Minotti L, et al. Immunocytochemical investigation on dysplastic human tissue from epileptic patients. Epilepsy Res 1998;32:3448.
  • 100
    Marco P, Sola RG, Pulido P, et al. Inhibitory neurons in the human epileptogenic temporal cortex: an immunocytochemical study. Brain 1996;119:132747.
  • 101
    Babb TL, Ying Z, Hadam J, Penrod C. Glutamate receptors in human epileptic dysplastic cortex. Epilepsy Res 1998;32:2433.
  • 102
    Ying Z, Babb TL, Comair YG, Bingaman W, Bushey M, Touhalsky K. Induced expression of NMDAR2 proteins and differential expression of NMDAR1 splice variants in dysplastic neurons of human epileptic cortex. J Neuropathol Exp Neurol 1998;57:4762.
  • 103
    Li LM, Dubeau F, Andermann F, et al. Periventricular nodular heterotopia and intractable temporal lobe epilepsy: poor outcome after temporal lobe resection. Ann Neurol 1997;41:6628.
  • 104
    Li LM, Cendes F, Bastos AC, Andermann F, Dubeau F, Arnold DL. Neuronal metabolic dysfunction in patients with cortical malformations: a proton magnetic resonance spectroscopic imaging study. Neurology 1998;50:7559.
  • 105
    Richardson MP, Koepp MJ, Brooks DJ, et al. Cerebral activation in malformations of cortical development. Brain 1998;121:1295304.
  • 106
    Jacobs KM, Gutnick MJ, Prince DA. Hyperexcitability in a model of cortical maldevelopment. Cerebr Cortex 1996;6:51423.
  • 107
    Hablitz JJ, DeFazio T. Excitability changes in freeze-induced cortical microgyria. Epilepsy Res 1998;32:7882.
  • 108
    Luhmann HJ, Raabe K. Characterization of neuronal migration disorders in neocortical structures: I. Expression of epileptiform activity in an animal model. Epilepsy Res 1996;26:6774.
  • 109
    Luhmann HJ, Raabe K, Zilles K. Characterization of neuronal migration disorders in neocortical structures: extracellular in vitro recordings. Eur J Neurosci 1998;10:308594.
  • 110
    Jacobs KM, Prince DA. Chronic focal neocortical epileptogenesis: does disinhibition play a role Can J Physiol Pharmacol 1997;75:5007.
  • 111
    Luhmann HJ, Karpuk N, Qü M, Zilles K. Characterization of neuronal migration disorders in neocortical structures. II. Intracellular in vitro recordings. J Neurophysiol 1998;80:92102.
  • 112
    Humphreys P. Rosen GD, Press DM, Sherman GF, Galaburda AM. Freezing lesion of the developing rat brain: a model for cerebrocortical microgyria. J Neuropathol Exp Neurol 1991;50:14560.
  • 113
    Jacobs KM, Mogensen M, Warren L, Prince DA. Experimental microgyri disrupt the cytochrome oxidase identified barrel formation in rat somatosensory cortex [Abstract]. Soc Neurosci Abstr 1997;317:5.
  • 114
    Rosen GD, Galaburda AM. Thalamocortical and corticothalamic connectivity in induced neocortical microgyria [Abstract]. Soc Neurosci Abstr 1998;224:12.
  • 115
    Rosen GD, Galaburda AM, Sherman GF. Cerebrocortical micro-dysgenesis with anomalous callosal connections: a case study in the rat. Int J Dev Neurosci 1989;47:23747.
  • 116
    Salin P, Tseng G-F, Hoffman S, Parada I, Prince DA. Axonal sprouting in layer V pyramidal neurons of chronically injured cerebral cortex. J Neurosci 1995;15:823445.
  • 117
    Marin-Padilla M. Developmental neuropathology and impact of perinatal brain damage. II: White matter lesions of the neocortex. J Neuropathol Exp Neurol 1997;56:21935.
  • 118
    Marin-Padilla M. Developmental neuropathology and impact of perinatal brain damage. I: Hemorrhagic lesions of the neocortex. J Neuropathol Exp Neurol 1996;55:75973.
  • 119
    Colacitti C, Sancini G, Franceschetti S, et al. Altered connections between neocortical and heterotopic areas in methylazoxymethanol-treated rats. Epilepsy Res 1998;32:4962.
  • 120
    Chevassus-au-Louis N, Congar P, Represa A, Ben-Ari Y, Gaiarsa J-L. Neuronal migration disorders: heterotopic neocortical neurons in CA1 form a bridge between the hippocampus and the neocortex. Proc Natl Acad Sci U S A 1998;95:102638.
  • 121
    Chevassus-au-Louis N, Ben-Ari Y, Vergnes M. Decreased seizure threshold and more rapid kindling in rats with prenatal treatment with methylzoxymethanol. Brain Res 1998;812:4225.
  • 122
    Holmes GL, Sarkisian MS, Ben-Ari Y, Chevassus-au-Louis N. Consequences of cortical microdysgenesis during development. Epilepsia 1998 (in press).
  • 123
    Represa A, Niquet J, Pollard H, Ben-Ari Y. Cell death, gliosis and synaptic remodeling in the hippocampus of epileptic rats. J Neurobiol 1995;26:41325.
  • 124
    Super H, Pérez Sust P, Soriano E. Survival of Cajal-Retzius cells after cortical lesions in newborn mice: a possible role for Cajal-Retzius cells in brain repair. Dev Brain Res 1997;98:914.
  • 125
    Marin-Padilla M. Cajal-Retzius cells and the development of the neocortex. Trends Neurosci 1998;21:6471.
  • 126
    Zilles K, Qü M, Schleicher A, Luhmann HJ. Characterization of neuronal migration disorders in neocortical structures: quantitative receptor autoradiography of ionotropic glutamate, GABAA and GABAB receptors. Eur J Neurosci 1998;10:3095106.
  • 127
    Baraban SC, Schwartzkroin PA. Electrophysiology of CA1 pyramidal neurons in an animal model of neuronal migration disorders: prenatal methylazoxymethanol treatment. Epilepsy Res 1995;22:14556.
  • 128
    Sancini G, Franceschetti S, Battaglia G, et al. Dysplastic neocortex and subcortical heterotopias in methylazoxymethanol-treated rats: an intracellular study of identified pyramidal neurons. Neurosci Lett 1998;246:1815.
  • 129
    Rafiki A, Chevassus-au-Louis N, Ben-Ari Y, Khrestchatisky M, Represa A. Glutamate receptors in dysplasic cortex: an in situ hybridization and immunohistochemical study in rats with prenatal treatment with methylazoxymethanol. Brain Res 1998;782:14252.
  • 130
    Johnston MV, Coyle JT. Cytotoxic lesions and the development of transmitter systems. Trends Neurosci 1982;5:1536.
  • 131
    Chauvel P, Trottier S, Ward AA, Woodbury DM, Porter RJ. Role of noradrenergic ascending system in extinction of epileptic phenomena. In: Delgado-EscuetaAV, ed. Basic mechanisms of the epilepsies, molecular and cellular approaches. New York : Raven Press, 1986:47587.
  • 132
    Trottier S, Evrard B, Biraben A, Chauvel P. Altered patterns of catecholaminergic fibers in focal cortical dysplasia in two patients with partial seizures. Epilepsy Res 1994;19:16179.
  • 133
    Meencke HJ, Janz D. The significance of microdysgenesis in primary generalized epilepsy: an answer to the considerations of Lyon and Gastaud. Epilepsia 1985;26:36871.
  • 134
    Meencke HJ. The density of dystopic neurons in the white matter of the gyrus frontalis inferior in epilepsies. J Neurol 1983;230:17881.
  • 135
    Lyon G, Gastaud H. Considerations on the significance attributed to unusual cerebral histological findings recently described in eight patients with primary generalized epilepsy. Epilepsia 1985;26:3657.
  • 136
    Emery JA, Roper SN, Rojiani AM. White matter neuronal heterotopia in temporal lobe epilepsy: a morphometric and immunohistochemical study. J Neuropathol Exp Neurol 1997;56:127682.
  • 137
    Bordarier C, Robain O, Rethoré M-O, Dulac O, Dhellemes C. Inverted neurons in agyria: a Golgi study of a case with abnormal chromosome 17. Hum Genet 1986;73:3748.
  • 138
    Steward R, Richman D, Caviness VS Jr. Lissencephaly and pachygyria: an architectonic and topographical analysis. Acta Neuropathol 1975;31:112.
  • 139
    Harding BN. Gray matter heterotopia. In: GuerriniR, AndermannE, CanapicchiR, RogerJ, ZilfkinB, PfannerP, eds. Dysplasias of the cerebral cortex and epilepsy. Philadelphia : Lippincott-Raven, 1996:818.
  • 140
    Lee KS, Chen Z-F, Schottler F, Bertram E. Spontaneous seizure activity in a rat with a genetic cortical heterotopia resembling the human syndrome of double cortex [Abstract]. Epilepsia 1996;37:S70.
  • 141
    Acampora D, Mazan S, Avantaggiato V, et al. Epilepsy and brain abnormalities in mice lacking the Otxl gene. Nature Genet 1996;14:21822.
  • 142
    Hirotsune S, Fleck MW, Gambello MJ, et al. Graded reduction o. Pafahlbl(Lisl) activity results in neuronal migration disorders defects and early embryonic lethality. Nature Genet 1998;19:3339.
  • 143
    Roper SN, Gilmore RL, Houser CR. Experimentally induced disorders of neuronal migration produce an increased propensity for electrographic seizures. Epilepsy Res 1995;21:20519.
  • 144
    Roper SN, King MA, Abraham LA, Boillot MA. Disinhibited in vitro neocortical slices containing experimentally induced cortical dysplasia demonstrate hyperexcitability. Epilepsy Res 1997;26:4439.
  • 145
    Baraban SC, McCarthy EB, Schwartzkroin PA. Evidence for increased seizure susceptibility in rats exposed to cocaine in utero. Dev Brain Res 1997;102:18996.
  • 146
    Snyder-Keller AM, Keller RW. Prenatal cocaine alters later sensitivity to cocaine-induced seizures. Neurosci Lett 1995;191:14952.