• 1
    Jay V, Becker LE. Surgical pathology of epilepsy: a review. Pediatr Pathol 1994;14:73150.
  • 2
    Ying Z, Babb TL, Comair YG, Bingaman W, Bushey M, Touhalisky K. Induced expression of NMDAR2 proteins and differential expression of NMDAR1 splice variants in dysplastic human epileptic neocortex. J Neuropathol Exp Neurol 1998;57:4762.
  • 3
    Hirabayashi S, Binnie CD, Janota I, Polkey CE. Surgical treatment of epilepsy due to cortical dysplasia: clinical and EEG findings. J Neurol Neurosurg Psychiatry 1993;56:76570.
  • 4
    Palmini A, Gambardella A, Andermann F, et al. Intrinsic epileptogenicity of human dysplastic cortex as suggested by corticography and surgical results. Ann Neurol 1995;37:47687.
  • 5
    Spreafico R, Battaglia G, Arcelli P, et al. Cortical dysplasia: an immunocytochemical study of three patients. Neurology 1998;50:2736.
  • 6
    Moriyoshi K, Masu M, Ishii T, Shigemoto R, Mizuno N, Nakanishi S. Molecular cloning and characterization of the rat NMDA receptor. Nature 1991;354:317.
  • 7
    Johnson HW, Ascher P. Glycine potentiates the NMDA response in cultured mouse brain neurons. Nature 1987;325:52931.
  • 8
    Kleckner NW, Dingledine R. Requirement for glycine in activation of NMDA-receptors expressed i Xenopus oocytes. Science 1988;241:8357.
  • 9
    Benveniste M, Mayer ML. Kinetic analysis of antagonist action a. N-methyl-D-aspartic acid receptors: two binding sites each for glutamate and glycine. Biophys J 1991;59:56073.
  • 10
    Clements JD, Westbrook GL. Activation kinetics reveal the number of glutamate and glycine binding sites on th.N-methyl-D-aspartate receptor. Neuron 1991;4:60513.
  • 11
    Brose N, Gasic GP, Vetter DE, Sullivan JM, Heinemann SF. Protein chemical characterization and immunocytochemical localization of the NMDA receptor subunit NMDA R1. J Biol Chem 1993;268:2266371.
  • 12
    Huh KH, Wenthold RJ. Turnover analysis of glutamate receptors identifies a rapidly degraded pool of th. N-methyl-D-aspartate receptor subunit, NR1, in cultured cerebellar granule cells. J Biol Chem 1999;274:1517.
  • 13
    Laube B, Hirai H, Sturgess M, Betz H, Kuhse J. Molecular determinants of agonist discrimination by NMDA receptor subunits: analysis of the glutamate binding site on the NR2B subunit. Neuron 1997;18:493503.
  • 14
    Laube B, Huhse J, Betz H. Evidence for a tetrameric structure of recombinant NMDA receptors. J Neurosci 1998;18:295461.
  • 15
    Morris HH III. Summary of epilepsy surgery protocols. In: LüdersHO, ed. Epilepsy surgery. New York : Raven Press, 1992:7868.
  • 16
    Babb TL, Pretorius JK, Kupfer WR, Crandall PH. Glutamate decarboxylase-immunoreactive neurons are preserved in human epileptic hippocampus. N Neurosci 1989;9:256274.
  • 17
    Rorke LB. A perspective: the role of disordered genetic control of neurogenesis in the pathogenesis of migration disorders. J Neuropathol Exp Neurol 1994;53:10517.
  • 18
    Mathern GW, Leite JP, Babb TL, et al. Aberrant hippocampal mossy fiber sprouting correlates with greater NMDAR2 receptor staining. Neuroreport 1996;7:102935.
  • 19
    Mikuni N, Babb TL, Chakravarty D, Hadam J, Penrod C. NMDAR2 upregulation precedes mossy fiber sprouting in kainate rat hippocampal epilepsy. Neurosci Lett 1998;255:258.
  • 20
    Babb TL, Pereira-Leite J, Mathern GW, Pretorius JK. Kainic acid induced hippocampal seizures in rats: comparisons of acute and chronic seizures using intrahippocampal versus systemic injections. Ital J Neurol Sci 1995;16:3944.
  • 21
    Watanabe M, Inoue Y, Sakimura K, Mishina M. Developmental changes in distribution of NMDA receptor channel subunit mRNAs. Neuroreport 1992;3:113840.
  • 22
    Sheng M, Cummings J, Roldan LA, Jan YN, Jan LY. Changing subunit composition of heteromeric NMDA receptors during development of rat cortex. Nature 1994;368:1447.