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Frontal Nonconvulsive Status Epilepticus Associated with High-Dose Tiagabine Therapy in a Child with Familial Bilateral Perisylvian Polymicrogyria

  1. P. Piccinelli1,
  2. R. Borgatti2,
  3. E. Perucca3,
  4. A. Tofani1,
  5. G. Donati1,
  6. U. Balottin1,*

Article first published online: 2 AUG 2005

DOI: 10.1111/j.1528-1157.2000.tb00126.x

Issue

Epilepsia

Epilepsia

Volume 41, Issue 11, pages 1485–1488, November 2000

Additional Information

How to Cite

Piccinelli, P., Borgatti, R., Perucca, E., Tofani, A., Donati, G. and Balottin, U. (2000), Frontal Nonconvulsive Status Epilepticus Associated with High-Dose Tiagabine Therapy in a Child with Familial Bilateral Perisylvian Polymicrogyria. Epilepsia, 41: 1485–1488. doi: 10.1111/j.1528-1157.2000.tb00126.x

Author Information

  1. 1

    Child Neuropsychiatry Unit, University of Insubria, “Fondazione Macchi” Hospital, Varese, Italy

  2. 2

    Department of Child Neuropsychiatry, Scientific Institute “Eugenio Medea,” Bosisio Parini, Italy

  3. 3

    Clinical Pharmacology Unit, University of Pavia, Italy

*Address correspondence and reprint requests to Prof. Umberto Balottin at Unità Operativa di Neuropsichiatria Infantile, Reparto Day Hospital, Ospedale “Filippo Del Ponte,” Piazza Biroldi, 19, 21100 Varese, Italy. E-mail: ppiccine@tin.it

Publication History

  1. Issue published online: 2 AUG 2005
  2. Article first published online: 2 AUG 2005
  3. Accepted June 26, 2000

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REFERENCES

  • 1
    Guerrini R, Belmonte A, Genton P., Antiepileptic drug-induced worsening of seizures in children. Epilepsia 1998;39(suppl 3):S2–10.
    Direct Link:
  • 2
    Perucca E, Gram L, Avanzini G, Dulac O., Antiepileptic drugs as a cause of worsening of seizures. Epilepsia 1998;39:5–17.
    Direct Link:
  • 3
    Schapel G, Chadwick D., Tiagabine and nonconvulsive status epilepticus. Seizure 1996;5:153–6.
  • 4
    Shinnar S, Treiman D, Sommerville K, et al. Evaluation of spike and wave discharges and complex partial status epilepticus in association with tiagabine therapy. Neurology 1997;48:A39.
  • 5
    Ettinger AB, Bernal OG, Andriola MR, et al. Two cases of nonconvulsive status epilepticus in association with tiagabine therapy. Epilepsia 1999; 40:1159–62.
    Direct Link:
  • 6
    Eckardt KM, Steinhoff BJ, Nonconvulsive status epilepticus in two patients receiving tiagabine treatment. Epilepsia 1998; 39:671–4.
    Direct Link:
  • 7
    Leppik IE, Gram L, Deaton R, Sommerville KW, Safety of tiagabine: summary of 53 trials. Epilepsy Res 1999;33:235–46.
  • 8
    Trinka E, Moroder T, Nagler M, Staffen W, Loscher W, Ladurner G., Clinical and EEG findings in complex partial status epilepticus with tiagabine. Seizure 1999;8:41–4.
  • 9
    Borgatti R, Triulzi F, Zucca C, et al. Bilateral perisylvian polymicrogyria in three generations. Neurology 1999; 52:1910–3.
  • 10
    Thomas P, Zifkin B, Migneco O, Lebrun C, Darcourt J, Andermann F., Nonconvulsive status epilepticus of frontal origin. Neurology 1999; 52:1174–83.
  • 11
    Tagawa T, Itagaki Y, Kobayashi M, Sano T, Sumi K., Nonconvulsive status epilepticus in a child with congenital bilateral perisylvian syndrome. Pediatr Neurol 1999;21:579–82.
  • 12
    Ohtsuka Y, Sato M, Oka E., Nonconvulsive status epilepticus in childhood localization-related epilepsy. Epilepsia 1999; 40:1003–10.
    Direct Link:
  • 13
    Walton NY, Gunawan S, Treiman DM, Treatment of experimental status epilepticus with GABA uptake inhibitor, tiagabine. Epilepsy Res 1994; 19:237–44.
  • 14
    Knake S, Hamer HM, Schomburg U, Oertel WH, Rosenow F., Tiagabine-induced absence status in idiopathic generalized epilepsy. Seizure 1999; 8:314–7.
  • 15
    Adkins JC, Noble S. Tiagabine A review of its pharmacodynamic and pharmacokinetic properties and therapeutic potential in the management of epilepsy. Drugs 1998; 55:437–62.
  • 16
    Jackson MF, Esplin B, Capek R., Activity-dependent enhancement of hyperpolarizing and depolarizing gamma-aminobutyric acid (GABA) synaptic responses following inhibition of GABA uptake by tiagabine. Epilepsy Res 1999; 37:25–36.
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