SEARCH

SEARCH BY CITATION

References

  • 1
    Gardocki, JF, Labinsky, LS, Brown, GL, Maryanoff, BE. Anticonvulsant activity of McN-4853 (M) (2,3:4,5-bis-O-[1-methylethylidene]-β-d-fructopyranose sulfamate in mice and rats. Epilepsia 1986;27:6489.
  • 2
    Maryanoff, BE, Nortey, SO, Gardocki, JF, Shank, RP, Dodgson, SP. Anticonvulsant O-alkyl sulfamates: 2,3:4,5-bis-O-(1-methylethylidene)-(β-d-fructopyranose sulfamate and related compounds. J Med Chem 1987;30:8807.
  • 3
    Shank, RP, Gardocki, JF, Vaught, JL, et al. Topiramate: preclinical evaluation of a structurally novel anticonvulsant. Epilepsia 1994;35:45060.
  • 4
    Dodgson, SJ, Shank, RP, Maryanoff, BE. Topiramate as an inhibitor of carbonic anhydrase isozymes. Epilepsia 2000;41(suppl 1):S359.
    Direct Link:
  • 5
    White, HS, Brown, SD, Woodhead, JH, Skeen, GA, Wolf, HH. Topiramate modulates GABA-evoked currents in murine cortical neurons by a nonbenzodiazepine mechanism. Epilepsia 2000;41(suppl 1):S1720.
  • 6
    Nakamura, J, Tamura, S, Kanda, T, Ishii, A, Ishihara, K, Serikawa, T, Yamada, J, Sasa, M. Inhibition by topiramate of seizures in spontaneously epileptic rats and DBA/2 mice. Eur J Pharmacol 1994;254:839.
  • 7
    Edmonds, HL Jr., Jiang, YD, Zhang, PY, Shank, RP. Anticonvulsant activity of topiramate and phenytoin in a rat model of ischemia-induced epilepsy. Life Sci 1996;59:PL12731.
  • 8
    Wauquier, A, Zhou, S. Topiramate: a potent anticonvulsant in the amygdala-kindled rat. Epilepsy Res 1996;24:737.
  • 9
    Streeter, AJ, Stahle, PL, Hills, JF, et al. Pharmacokinetics of topiramate in the rat. Pharm Res 1994;11(suppl):S372.
  • 10
    Easterling, DE, Zakszewski, T, Moyer, MD, et al. Plasma pharma-cokinetics of topiramate, a new anticonvulsant, in humans. Epilepsia 1988;29(suppl):662.
  • 11
    Sachdeo, RC, Sachdeo, SK, Walker, SA, Kramer, LD, Nayak, RK, Doose, DR. Steady-state pharmacokinetics of topiramate and carbamazepine in patients with epilepsy during monotherapy and concomitant therapy. Epilepsia 1996;37:77480.
  • 12
    Streeter, AJ, Wu, WN, Stahle, PL, et al. An in vivo interaction between topiramate and phenytoin in the Sprague-Dawley rat. ISSX Proc 1995;8:305.
  • 13
    Streeter, AJ, Stahle, PL, Holland, ML, et al. Pharmacokinetics and bioavailability of topiramate in the beagle dog. Drug Metab Dispos 1995;23:903.
  • 14
    Wu, WN, McKown, LA, Takacs, AR, et al. Metabolism of the an-ticonvulsant, topiramate, in mouse, rat, rabbit, dog, and human. Proceedings of the 42nd ASMS Conference on Mass Spectrometry and Allied Topics, June 3, 1994. Chicago , Illinois , 59.
  • 15
    Wu, WN, Heebner, JB, Streeter, AJ. Evaluation of the absorption, excretion, pharmacokinetics and metabolism of the anticonvulsant, topiramate, in healthy men. Pharm Res 1994;11(suppl):S336.
  • 15a
    Nortey, SO, Wu, WN, Maryanoff, BE. Synthesis of hydroxylated derivatives of topiramate, a novel antiepileptic drug based on D-fructose: Investigation of oxidative metabolites. Carbohydrate Research 1997;304, 2938.
  • 16
    Sills, GE, Leach, JP, Kilpatrick, WS, et al. Concentration-effect studies with topiramate on selected enzymes and intermediates of the GABA shunt. Epilepsia 2000;41(suppl 1):S304.
    Direct Link:
  • 17
    DeLorenzo, RJ, Sombati, S, Coulter, DA. Effects of topiramate on sustained repetitive firing and spontaneous recurrent seizure discharges in cultured hippocampal neurons. Epilepsia 2000;41(suppl 1):S404.
    Direct Link:
  • 18
    Pina-Garza, JE, McLean, MJ. Different effects of topiramate and phenytoin on mouse seizures and responses of cultured neurons to excitatory amino acids. Epilepsia 1996;37(suppl 5):26.
  • 19
    Rogawski, MA, Porter, RJ. Antiepileptic drugs: pharmacological mechanisms and clinical efficacy with consideration of promising developmental stage compounds. Pharmacol Rev 1990;42:22386.
  • 20
    Macdonald, RL, McLean, MJ. Anticonvulsant drugs: mechanisms of action. In: Delgado-Escueta, AV, Ward, AA, Woodbury, DM, Porter, RJ, eds. Advances in Neurology. Vol IV. New York : Raven Press, 1986:71336.
  • 21
    Zona, C, Ciotti, MT, Avoli, M. Topiramate attenuates voltage-gated sodium currents in rat cerebellar granule cells in culture. Neurosci Lett 1997;231:1236.
  • 22
    McLean, MJ, Bukhari, AA, Wamil, AW. Effects of topiramate on sodium-dependent action potential firing by mouse spinal cord neurons in cell culture. Epilepsia 2000;41(suppl 1):S214.
  • 23
    Taverna, S, Sancini, G, Mantegazza, M, Franceschetti, S, Avanzini, G. Inhibition of transient and persistent Na+ current fractions by the new anticonvulsant topiramate. J Pharmacol Exp Ther 1999;288:9608.
  • 24
    Wu, SP, Tsai, JJ, Gean, PW. Frequency-dependent inhibition of neuronal firing by topiramate in hippocampal slices. Br J Pharmacol 1999;125:82632.
  • 25
    Brown, SD, Wolf, HH, Swinyard, EA, Twyman, RE, White, HS. The novel anticonvulsant topiramate enhances GABA-mediated chloride flux. Epilepsia 1993;34(suppl 2):122.
  • 26
    White, HS, Brown, SD, Woodhead, JH, Skeen, GA, Wolf, HH. Topiramate enhances GABA-mediated chloride flux and GABA-evoked currents in mouse brain neurons and increases seizure threshold. Epilepsy Res 1997;28:16779.
  • 27
    Deleted in proof.
  • 28
    Gordey, M, DeLorey, TM, Olsen, RW. Differential sensitivity of recombinant GABAA receptors expressed in Xenopus oocytes to modulation by topiramate. Epilepsia 2000;41(suppl 1):S259.
  • 29
    Gibbs, JW, Sombati, S, DeLorenzo, RJ, Coulter, DA. Cellular actions of topiramate: blockade of kainate-evoked inward currents in cultured hippocampal neurons. Epilepsia 2000;41(suppl 1):S106.
  • 30
    Skradski, S, White, HS. Topiramate blocks kainate-evoked cobalt influx into cultured neurons. Epilepsia 2000;41(suppl 1):S457.
  • 31
    Zhang, XL, Velumian, A, Jones, OT, Carlen, PL. Modulation of high voltage-activated calcium channels in dentate granule cells by topiramate. Epilepsia 2000;41(suppl 1):S5260.
  • 32
    Anderson, RE, Chiu, P, Woodbury, DM. Mechanisms of tolerance to the anticonvulsant effects of acetazolamide in mice: relation to the activity and amount of carbonic anhydrase in brain. Epilepsia 1989;30:20816.
  • 33
    Lee, J, Taira, T, Pihlaja, P, Ransom, BR, Kaila, K. Effects of CO2 on excitatory transmission apparently caused by changes in intracellular pH in the rat hippocampal slice. Brain Res 1996;706:2106.
  • 34
    Taira, T, Lamsa, K, Kaila, K. Posttetanic excitation mediated by GABA(A) receptors in rat CA1 pyramidal neurons. J Neurophysiol 1997;77:22138.
  • 35
    Staley, KJ, Soldo, BL, Proctor, WR. Ionic mechanisms of neuronal excitation by inhibitory GABAA receptors. Science 1995;269:97781.
  • 36
    Krebs, EG. The growth of research on protein phosphorylation. Trends Biochem Sci 1994;19:439.
  • 37
    Roche, KW, O'Brien, RJ, Mammen, AL, Bernhardt, J, Huganir, RL. Characterization of multiple phosphorylation sites on the AMPA receptor GluR1 subunit. Neuron 1996;16:117988.
  • 38
    Wang, JH, Kelly, PT. Postsynaptic injection of Ca2+/CaM induces synaptic potentiation requiring CaMKII and PKC activity. Neuron 1995;15:44352.
  • 39
    Sigel, E. Functional modulation of ligand-gated GABAA and NMDA receptor channels by phosphorylation. J Recept Signal Transduct Res 1995;15:32532.
  • 40
    Smith, L, Price-Jones, M, Hughes, K, et al. Effects of topiramate on kainate-and domoate-activated [14C]guanidinium ion flux through GluR6 channels in transfected BHK cells using Cytostar-T santillating microplates. Epilepsia 2000;41(suppl 1):S4851.