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Seizures in multiple sclerosis

  1. Marcus Koch,
  2. Maarten Uyttenboogaart,
  3. Susan Polman,
  4. Jacques De Keyser

Article first published online: 11 MAR 2008

DOI: 10.1111/j.1528-1167.2008.01565.x

Issue

Epilepsia

Epilepsia

Volume 49, Issue 6, pages 948–953, June 2008

Additional Information

How to Cite

Koch, M., Uyttenboogaart, M., Polman, S. and De Keyser, J. (2008), Seizures in multiple sclerosis. Epilepsia, 49: 948–953. doi: 10.1111/j.1528-1167.2008.01565.x

Author Information

  1. Neurology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands

*Address correspondence to Marcus Koch, M.D., Department of Neurology, University Medical Center Groningen, Hanzeplein 1, 9713 GZ Groningen, The Netherlands. E-mail: m.w.koch@neuro.umcg.nl

Publication History

  1. Issue published online: 11 MAR 2008
  2. Article first published online: 11 MAR 2008
  3. Accepted January 27, 2008; Online Early publication March 11, 2008.

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Keywords:

  • Multiple sclerosis;
  • Seizure;
  • Epilepsy;
  • Convulsions;
  • Treatment

Summary

Seizures have long been recognized to be part of the disease spectrum of multiple sclerosis (MS). While they occur in only a minority of patients with MS, epileptic seizures can have serious consequences. The treatment of MS can be epileptogenic, and antiepileptic treatment can conversely worsen the symptoms of MS. In this article we present an overview of the current literature on the epidemiology, clinical presentation, pathology, imaging, prognosis and treatment of epileptic seizures in MS.

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