Gelastic seizures and the anteromesial frontal lobe: A case report and review of intracranial EEG recording and electrocortical stimulation case studies
Article first published online: 19 MAR 2010
Wiley Periodicals, Inc. © 2010 International League Against Epilepsy
Volume 51, Issue 10, pages 2195–2198, October 2010
How to Cite
Unnwongse, K., Wehner, T., Bingaman, W. and Foldvary-Schaefer, N. (2010), Gelastic seizures and the anteromesial frontal lobe: A case report and review of intracranial EEG recording and electrocortical stimulation case studies. Epilepsia, 51: 2195–2198. doi: 10.1111/j.1528-1167.2010.02548.x
- Issue published online: 19 MAR 2010
- Article first published online: 19 MAR 2010
- Accepted January 18, 2010; Early View publication March 19, 2010.
- Gelastic seizure;
- Frontal lobe;
- Intracranial EEG recording;
- Electrocortical stimulation
Symptomatogenic areas for ictal laughter have been described in the frontal and temporal lobes. Within the frontal lobe, gelastic seizures have been recorded from the cingulate gyrus. Electrocortical stimulation of the cingulate gyrus as well as the superior frontal gyrus induced laughter. We describe a patient whose gelastic seizures were associated with electrographic ictal activity in the mesial aspect of the right anterior frontal gyrus. The symptomatogenic area for ictal laughter in the frontal lobe may reside in the superior frontal gyrus.